高级搜索

2014年北京市居民母乳中二英及其类似物负荷水平

,  ,  ,  ,  ,  ,  , 

downloadPDF

上一篇

下一篇

鲍彦, 王珊, 池敏, 张磊, 孟桂敏, 李敬光, 赵云峰, 吴永宁. 2014年北京市居民母乳中二英及其类似物负荷水平[J]. 环境化学, 2016, 35(4): 732-738. doi: 10.7524/j.issn.0254-6108.2016.04.2015111804
引用本文: 鲍彦, 王珊, 池敏, 张磊, 孟桂敏, 李敬光, 赵云峰, 吴永宁. 2014年北京市居民母乳中二英及其类似物负荷水平[J]. 环境化学, 2016, 35(4): 732-738. doi: 10.7524/j.issn.0254-6108.2016.04.2015111804
shu
BAO Yan, WANG Shan, CHI Min, ZHANG Lei, MENG Guimin, LI Jingguang, ZHAO Yunfeng, WU Yongning. Dioxin-like compounds in human milk samples in Beijing, 2014[J]. Environmental Chemistry, 2016, 35(4): 732-738. doi: 10.7524/j.issn.0254-6108.2016.04.2015111804
Citation: BAO Yan, WANG Shan, CHI Min, ZHANG Lei, MENG Guimin, LI Jingguang, ZHAO Yunfeng, WU Yongning. Dioxin-like compounds in human milk samples in Beijing, 2014[J]. Environmental Chemistry, 2016, 35(4): 732-738. doi: 10.7524/j.issn.0254-6108.2016.04.2015111804
shu

2014年北京市居民母乳中二英及其类似物负荷水平

  • 1.

    国家食品安全风险评估中心, 卫生部食品安全风险评估重点实验室, 北京, 100021;

  • 2.

    山西医科大学, 太原, 030001;

  • 3.

    北京市西城区妇幼保健院, 北京, 100054

  • 基金项目:

    国家自然科学基金国际合作项目(21361140359)

    中国科学院战略性先导科技专项子课题(XDB14010101)资助.

Dioxin-like compounds in human milk samples in Beijing, 2014

  • 1.

    Key Laboratory of Food Safety Risk Assessment, Ministry of Health, China National Center for Food Safety Risk Assessment, Beijing, 100021, China;

  • 2.

    Shanxi Medical University, Taiyuan, 030001, China;

  • 3.

    Xicheng District Maternal and Children Health Hospital, Beijing, 100054, China

  • Fund Project: Supported by the National Natural Science Foundation of China(21361140359)and the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB14010101).

  • 摘要: 本研究于2014年在北京市采集母乳样品37份,按照国标方法采用高分辨气相色谱-高分辨质谱(HRGC-HRMS)结合同位素稀释技术,测定样品中二英及其类似物含量.总毒性当量的均值为6.74 pg TEQ·g-1脂肪,多氯代苯并呋喃(PCDD/Fs)和二英样多氯联苯(dl-PCBs)毒性当量的均值分别为5.06 pg TEQ·g-1 脂肪和1.68 pg TEQ·g-1 脂肪.与发达国家和地区相比,北京市普通人群的二英及其类似物负荷水平较低.
    Abstract: Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (dl-PCBs) in 37 human milk samples collected in 2014 from Beijing residents were determined by high-resolution gas chromatography-high resolution mass spectrometry (HRGC-HRMS) and isotope dilution methodology. The mean valuesof TEQ, based on WHO TEFs 1998, were 5.06pg TEQ·g-1 fat for PCDD/Fs and 1.68 pg TEQ·g-1 fat for dl-PCBs,giving a total of 6.74 pg TEQ·g-1 fatfor PCDD/Fs plus dl-PCBs.The TEQ body burdens of the people living in Beijing were lower than those in the developed countries.
  • 加载中
  • [1] CANADY R, CRUMP K, FEELEY M, et al. Safety evaluation of certain food additives and contaminants: Polychlorinated dibenzodioxins, Polychlorinated dibenzofurans, coplanar polychlorinated biphenyls[J]. WHO Food Additives Series, 2001, 48.
    [2] KOGEVINAS M. Human health effects of dioxins: Cancer, reproductive and endocrine system effects[J]. Human Reproduction Update, 2001. 7(S103): 331-339.
    [3] 吴永宁, 二英、多氯联苯和氯丙醇的痕量与超痕量检测技术研究[J]. 中国食品卫生杂志, 2005,17(6): 481-486.

    WU Y N, Capability building in China for ultra-trace analysis of dioxin, PCBs and chloropropanols[J]. Chinese Journal of Food Hygiene, 2005, 17(6): 481-486 (in Chinese).

    [4] 吴永宁, 食品污染监测与控制技术[M]. 北京:化学工业出版社,2011. WU Y N, Technology of monitoring and control for food contamination[M]. Beijing: Chemical Industry Press, 2011(in Chinese).
    [5] LI J, ZHANG L, WU Y, et al. A national survey of polychlorinated dioxins, furans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (dl-PCBs) in human milk in China[J]. Chemosphere, 2009, 75(9): 1236-1242.
    [6] WHO. Fourth WHO-coordinated survey of human milk for persistent organicpollutants in cooperation with UNEP. Guidelines for Developing a National Protocol, World Health Organization[R]. 2007.
    [7]
    [8] VAND B M, BIRNBAUM L, BOSVELD A T, et al. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife[J]. Environmental Health Perspectives, 1998, 106(12): 775-792.
    [9] SHEN H, DING G, WU Y, et al. Polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs), polychlorinated biphenyls (PCBs), and polybrominateddiphenyl ethers (PBDEs) in breast milk from Zhejiang, China[J]. Environment International, 2012,42(42): 84-90.
    [10] DIRTU A C AND ADRIAN C. Estimation of daily intake of organohalogenated contaminants from food consumption and indoor dust ingestion in Romania[J]. Environmental Science & Technology, 2010, 44(16): 6297-6304.
    [11] TAO Z, HONG WEN S, QIAN W, et al. Perfluorochemicals in meat, eggs and indoor dust in China: Assessment of sources and pathways of human exposure to perfluorochemicals[J]. Environmental Science & Technology, 2010, 44(9): 3572-3579.
    [12] WHO. Environmental Health Series No 34: Levels of PCBs, PCDDs, and PCDFs in breast milk, WHO Regional Office for Europe, Copenhagen, Denmark[R]. 1989.
    [13] WHO. Environmental Health in Europe No. 3: Levels of PCBs, PCDDs, and PCDFs in human milk: second round of the WHO coordinated exposure study, WHO Regional Office for Europe, Copenhagen, Denmark[R]. 1996.
    [14] ROLAF V L F X AND RAINER M. Results of the third round of the who-coordinated exposure study on the levels of PCBS, PCDDS and PCDFS in human milk[J]. Organohalogen Compounds, 2002.
    [15] FOCANT J F, FRÉRY N, BIDONDO M L, et al. Levels of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polychlorinated biphenyls in human milk from different regions of France[J]. Science of the Total Environment, 2013, 452-453(5): 155-162.
    [16] CROES K, COLLES A, KOPPEN G, et al. Persistent organic pollutants (POPs) in human milk: A biomonitoring study in rural areas of Flanders (Belgium)[J]. Chemosphere, 2012,89(8): 988-994.
    [17] PRATT I S, ANDERSON W A, CROWLEY D, et al. Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in breast milk of first-time Irish mothers: Impact of the 2008 dioxin incident in Ireland[J]. Chemosphere, 2012, 88(7): 865-872.
    [18] Ryan J J and Rawn D F K, The brominated flame retardants, PBDEs and HBCD, in Canadian human milk samples collected from 1992 to 2005; Concentrations and trends[J]. Environment International, 2014,70: 1-8.
    [19] HARDEN F A, TOMS L M L, SYMONS R, et al. Evaluation of dioxin-like chemicals in pooled human milk samples collected in Australia[J]. Chemosphere, 2007, 67(9): S325-S333.
    [20] TODAKA T, HIRAKAWA H, KAJIWARA J, et al. Relationship between the concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and polychlorinated biphenyls in maternal blood and those in breast milk[J]. Chemosphere, 2010,78(2): 185-192.
    [21] HEDLEY A J, TZEWAI W, LING H L, et al. Breast milk dioxins in Hong Kong and Pearl River Delta[J]. Environmental Health Perspectives, 2006, 114(2): 202-208.
    [22] 张磊, 刘印平, 李敬光, 等. 2007 年北京市居民母乳中二英类化合物负荷水平调查[J]. 中华预防医学杂志, 2013, 47(6): 534-537.

    ZHANG L, LIU Y M, LI J G, et al. The human body burden of polychlorinated dibenzo-p-dioxins and dibenzofurans and dioxin-like polychlorinated biphenyls in residents' human breast milk from Beijing in 2007[J]. Chinese Journal of Preventive Medicine,2013, 47(6): 534-537(in Chinese).

    [23] FAROON O M AND KEITH L S. Polychlorinated biphenyls: Human health aspects[R]. Geneva World Health Organization, 2003, 55.
    [24] 毕新慧,徐晓白, 多氯联苯的环境行为[J]. 化学进展, 2000, 12(2): 152-160.

    BI X H, XU X B, Behaviors of PCBs in environment[J]. Progress in Chemistry, 2000, 12(2): 152-160(in Chinese).

  • 加载中
WeChat 点击查看大图
计量
  • 文章访问数:  671
  • HTML全文浏览数:  584
  • PDF下载数:  376
  • 施引文献:  0
出版历程
  • 收稿日期:  2015-11-18
  • 刊出日期:  2016-04-15

2014年北京市居民母乳中二英及其类似物负荷水平

  • 1.  国家食品安全风险评估中心, 卫生部食品安全风险评估重点实验室, 北京, 100021;
  • 2.  山西医科大学, 太原, 030001;
  • 3.  北京市西城区妇幼保健院, 北京, 100054
  • 收稿日期:  2015-11-18
基金项目:

国家自然科学基金国际合作项目(21361140359)

中国科学院战略性先导科技专项子课题(XDB14010101)资助.

摘要: 本研究于2014年在北京市采集母乳样品37份,按照国标方法采用高分辨气相色谱-高分辨质谱(HRGC-HRMS)结合同位素稀释技术,测定样品中二英及其类似物含量.总毒性当量的均值为6.74 pg TEQ·g-1脂肪,多氯代苯并呋喃(PCDD/Fs)和二英样多氯联苯(dl-PCBs)毒性当量的均值分别为5.06 pg TEQ·g-1 脂肪和1.68 pg TEQ·g-1 脂肪.与发达国家和地区相比,北京市普通人群的二英及其类似物负荷水平较低.

English Abstract

    全文HTML

参考文献 (24)

目录

/

返回文章
返回

Copyright © 2019 中国科学院生态环境研究中心