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新型冠状病毒2019-nCoV的一些初步认识

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詹菁, 刘倩, 张雨竹, 郝放, 梁勇, 曲广波, 胡立刚, 周群芳, 江桂斌. 新型冠状病毒2019-nCoV的一些初步认识[J]. 环境化学, 2020, (2): 283-291. doi: 10.7524/j.issn.0254-6108.2020021501
引用本文: 詹菁, 刘倩, 张雨竹, 郝放, 梁勇, 曲广波, 胡立刚, 周群芳, 江桂斌. 新型冠状病毒2019-nCoV的一些初步认识[J]. 环境化学, 2020, (2): 283-291. doi: 10.7524/j.issn.0254-6108.2020021501
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ZHAN Jing, LIU S. Qian, ZHANG Yuzhu, HAO Fang, LIANG Yong, QU Guangbo, HU Ligang, ZHOU Qunfang, JIANG Guibin. Preliminary understanding of the novel coronavirus 2019-nCoV[J]. Environmental Chemistry, 2020, (2): 283-291. doi: 10.7524/j.issn.0254-6108.2020021501
Citation: ZHAN Jing, LIU S. Qian, ZHANG Yuzhu, HAO Fang, LIANG Yong, QU Guangbo, HU Ligang, ZHOU Qunfang, JIANG Guibin. Preliminary understanding of the novel coronavirus 2019-nCoV[J]. Environmental Chemistry, 2020, (2): 283-291. doi: 10.7524/j.issn.0254-6108.2020021501
shu

新型冠状病毒2019-nCoV的一些初步认识

  • 1. 中国科学院生态环境研究中心环境化学与生态毒理学国家重点实验室, 北京, 100085;

  • 2. 中国科学院大学资源与环境学院, 北京, 100049;

  • 3. 江汉大学环境与健康研究院, 武汉, 430056

    • 通讯作者: 刘倩, E-mail: qianl@rcees.ac.cn ; 
  • 基金项目:

    国家自然科学基金（21806178）资助.

Preliminary understanding of the novel coronavirus 2019-nCoV

  • 1. State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China;

  • 2. College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China;

  • 3. Institute of Environment and Health, Jianghan University, Wuhan, 430056, China

    • Corresponding author: LIU S. Qian, qianl@rcees.ac.cn ; 
  • Fund Project: Supported by the National Natural Science Foundation of China (21806178)

  • 摘要:

    2019年12月，中国武汉市发生了由一种新型冠状病毒2019-nCoV（即SARS-CoV-2）感染导致的肺炎疫情.2019-nCoV经过传播导致疫病在全国甚至全世界范围内流行，严重危害了人类健康.为了控制病毒的传播、保障人民的健康和生命安全，医疗界、政府各部门和广大科研工作者全力以赴开展了病毒相关的研究和防控工作.本文整理了关于2019-nCoV的最新研究结果，总结了2019-nCoV的病原性特征、环境演化、传播途径、诊断方法、治疗对策，特别是从环境科学的角度探讨了环境因素对2019-nCoV传播的潜在影响，并针对目前尚未完全解决的问题提出了展望，以期加深人们对2019-nCoV的认知，并从医学、生物学、环境科学等不同角度启发针对2019-nCoV及其他相关病毒有效防控的科学思考.

    Abstract:

    In December 2019, an outbreak of pneumonia caused by a novel coronavirus called 2019-nCoV (SARS-CoV-2) occurred in Wuhan, China. Due to its high contagiousness and pathogenicity, this virus has led to an emerging epidemic that spreads throughout the whole country or even the world. The medical professionals, government departments and scientific researchers have made full efforts to carry out the clinical treatment, prevention, control work, and scientific studies about 2019-nCoV and its derived disease. This review summarized the latest knowledge on the characteristics, environmental evolution, and transmission route of 2019-nCoV. The diagnosis and treatment strategies for coronavirus disease 2019 (COVID-19) were sort out, and the potential environmental influencing factors and the perspectives for some unsolved problems were discussed. The article will help to improve the understanding of 2019-nCoV, and deepen the thinking about the prevention and control of 2019-nCoV and the related pathogenic virus from the aspects of medical care, biological and environmental science.

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  • [1] 李新华,高福. 新型冠状病毒感染的肺炎公众防护指南[M]. 北京:人民卫生出版社,2020. LI X H, GAO F. Guidelines for public protection against pneumonia from novel coronavirus infection[M]. Beijing:People's Medical Publishing House, 2020(in Chinese).
    [2] CUI J, LI F, SHI Z L, et al. Origin and evolution of pathogenic coronaviruses[J]. Nature Reviews Microbiology, 2019, 17:181-192.
    [3] ZHU N, ZHANG D Y, WANG W L, et al. A novel coronavirus from patients with pneumonia in China, 2019[J]. The New England Journal of Medicine, Published on January 24, 2020. DOI:10.1056/NEJMoa2001017
    [4] SANJUAN R, DOMINGO-CALAP P. Mechanisms of viral mutation[J]. Cellular and Molecular Life Sciences, 2016, 73(23):4433-4448.
    [5] 谢天恩,胡志红. 普通病毒学[M]. 北京:科学出版社,2002. XIE T E, HU Z H. General virology[M]. Beijing:Science Press, 2002(in Chinese).
    [6] ZIMMER C. A planet of viruses, the 2nd edition[M]. Chicago:The University of Chicago Press, 2015.
    [7] HOLLAND J, DOMINGO E. Origin and evolution of viruses[J]. Virus genes, 1998, 16(1):13-21.
    [8] 王雯姝,张中和. 环境污染与新的病毒传染病[J]. 医学与哲学,2004,25(5):18-19.

    WANG W S, ZHANG Z H. Environmental pollution and new viral infections[J]. Medicine & Philosophy, 2004, 25(5):18-19(in Chinese).

    [9] HOLMES E C, RAMBAUT A. Viral evolution and the emergence of SARS coronavirus[J]. Philosophical Transactions of the Royal Society of London. Series B:Biological Sciences, 2004, 359(1447):1059-1065.
    [10] RAJ V S, OSTERHAUS A D M E, FOUCHIER R A M, et al. MERS:Emergence of a novel human coronavirus[J]. Current Opinion in Virology, 2014, 5:58-62.
    [11] LU R J, ZHAO X, LI J, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus:Implications for virus origins and receptor binding[J]. The Lancet, published on January 29, 2020. DOI:10.1016/S0140-6736(20)30251-8
    [12] ZHOU P, YANG X L, WANG X G, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin[J]. Nature, published on February 03, 2020. DOI:10.1038/s41586-020-2012-7
    [13]
    [14] BELOUZARD S, MILLET J K, LICITRA B N, et al. Mechanisms of coronavirus cell entry mediated by the viral spike protein[J]. Viruses, 2012, 4(6):1011-1033.
    [15] HAMMING I, TIMENS W, BULTHUIS M L C, et al. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis[J]. The Journal of Pathology, 2004, 203(2):631-637.
    [16] XU X T, CHEN P, WANG J F, et al. Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission[J]. Science China Life Sciences, published on January 21, 2020. DOI:10.1007/s11427-020-1637-5
    [17] GUAN W J, NI ZY, HU Y, et al. Clinical characteristics of 2019 novel coronavirus infection in China[J]. medRxiv, 2020.02.06.20020974. https://doi.org/10.1101/2020.02.06.20020974
    [18] LU C W, LIU X F, JIA Z F. 2019-nCoV transmission through the ocular surface must not be ignored[J]. The Lancet, published on February 06, 2020. DOI:10.1016/S0140-6736(20)30313-5
    [19]
    [20] YU I T S, LI Y, WONG T W, et al. Evidence of airborne transmission of the severe acute respiratory syndrome virus[J]. The New England Journal of Medicine, 2004, 350(17):1731-1739.
    [21] CHAN J F W, YUAN S, KOK K H, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission:A study of a family cluster[J]. The Lancet, published on January 24, 2020. DOI:10.1016/S0140-6736(20)30154-9
    [22] 莫茜,秦炜,傅启华,等. 正确认识新冠病毒核酸检测的影响因素[J]. 中华检验医学杂志,2020,43:E002-E002. DOI:10.

    3760/cma.j.issn.1009-8158.2020.0002 MO X, QIN W, FU Q H, et al. Understanding the influence factors in viral nucleic acid test of 2019 novel coronavirus (2019-nCoV)[J], Chinese Journal of Laboratory Medicine, 2020, 43:E002-E002(in Chinese). DOI:10.3760/cma.j.issn.1009-8158.2020.0002

    [23] HOLSHUE L M, DEBOLT C, LINDQUIST S, et al. First case of 2019 novel coronavirus in the United States[J]. The New England Journal of Medicine, published on January 31, 2020. DOI:10.1056/NEJMoa2001191
    [24] WANG M, CAO R, ZHANG L, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro[J]. Cell Research, published on February 04, 2020. DOI:10.1038/s41422-020-0282-0
    [25]
    [26] 赵国胜,赵利淦. 环境因素对病毒存活的影响[J]. 预防医学情报杂志,1987,3(1):7-10.

    ZHAO G S, ZHAO L J. The influence of environmental factors on the survival of virus[J]. Journal of Preventive Medicine Information, 1987, 3(1):7-10(in Chinese).

    [27] TANG W J. The effect of environmental parameters on the survival of airborne infectious agents[J]. Journal of the Royal Society Interface, 2009, 6:S737-S746.
    [28] 刘鹏,张华玲,李丹. 人体飞沫室内传播的动力学特性[J]. 制冷与空调,2016,30(4):371-376.

    LIU P, ZHANG H L, LI D. Dynamic characteristics of human droplet indoor transmission[J]. Refrigeration and Air Conditioning, 2016, 30(4):371-376(in Chinese).

    [29] YE Q, FU J F, MAO J H, et al. Haze is an important medium for the spread of rotavirus[J]. Environmental Pollution, 2016, 216:324-331.
    [30] YE Q, FU J F, MAO J H, et al. Haze is a risk factor contributing to the rapid spread of respiratory syncytial virus in children[J]. Environmental Science and Pollution Research, 2016, 23:20178-20185.
    [31] 王新为,李劲松,金敏,等. SARS冠状病毒的抵抗力研究[J]. 环境与健康杂志,2004,21(2):67-71.

    WANG X W, LI J S, JIN M, et al. Study on resistance of SARS-Coronavirus[J]. Journal of Environment and Health, 2004, 21(2):67-71(in Chinese).

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  • 收稿日期:  2020-02-15
詹菁, 刘倩, 张雨竹, 郝放, 梁勇, 曲广波, 胡立刚, 周群芳, 江桂斌. 新型冠状病毒2019-nCoV的一些初步认识[J]. 环境化学, 2020, (2): 283-291. doi: 10.7524/j.issn.0254-6108.2020021501
引用本文: 詹菁, 刘倩, 张雨竹, 郝放, 梁勇, 曲广波, 胡立刚, 周群芳, 江桂斌. 新型冠状病毒2019-nCoV的一些初步认识[J]. 环境化学, 2020, (2): 283-291. doi: 10.7524/j.issn.0254-6108.2020021501
shu
ZHAN Jing, LIU S. Qian, ZHANG Yuzhu, HAO Fang, LIANG Yong, QU Guangbo, HU Ligang, ZHOU Qunfang, JIANG Guibin. Preliminary understanding of the novel coronavirus 2019-nCoV[J]. Environmental Chemistry, 2020, (2): 283-291. doi: 10.7524/j.issn.0254-6108.2020021501
Citation: ZHAN Jing, LIU S. Qian, ZHANG Yuzhu, HAO Fang, LIANG Yong, QU Guangbo, HU Ligang, ZHOU Qunfang, JIANG Guibin. Preliminary understanding of the novel coronavirus 2019-nCoV[J]. Environmental Chemistry, 2020, (2): 283-291. doi: 10.7524/j.issn.0254-6108.2020021501
shu

新型冠状病毒2019-nCoV的一些初步认识

    通讯作者: 刘倩, E-mail: qianl@rcees.ac.cn ; 
  • 1. 中国科学院生态环境研究中心环境化学与生态毒理学国家重点实验室, 北京, 100085;
  • 2. 中国科学院大学资源与环境学院, 北京, 100049;
  • 3. 江汉大学环境与健康研究院, 武汉, 430056
  • 收稿日期:  2020-02-15
  • 网络出版日期:  2019-12-02
基金项目:

国家自然科学基金（21806178）资助.

摘要: 

2019年12月，中国武汉市发生了由一种新型冠状病毒2019-nCoV（即SARS-CoV-2）感染导致的肺炎疫情.2019-nCoV经过传播导致疫病在全国甚至全世界范围内流行，严重危害了人类健康.为了控制病毒的传播、保障人民的健康和生命安全，医疗界、政府各部门和广大科研工作者全力以赴开展了病毒相关的研究和防控工作.本文整理了关于2019-nCoV的最新研究结果，总结了2019-nCoV的病原性特征、环境演化、传播途径、诊断方法、治疗对策，特别是从环境科学的角度探讨了环境因素对2019-nCoV传播的潜在影响，并针对目前尚未完全解决的问题提出了展望，以期加深人们对2019-nCoV的认知，并从医学、生物学、环境科学等不同角度启发针对2019-nCoV及其他相关病毒有效防控的科学思考.

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