广州市不同微环境室内灰尘中合成麝香分布及健康风险初步评价
Occurrence and distribution of synthetic musks in indoor dust in Guangzhou and their potential human health risk
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摘要: 本文采集了广州市不同微环境(居民家庭、办公室、化学前处理实验室和仪器房)室内灰尘45个,并研究了灰尘中9种合成麝香(synthetic musks,SMs)的含量与分布.灰尘中合成麝香总浓度(∑SMs)范围为17.6—1153 ng·g-1,在国内外处于较低水平,主要化合物为佳乐麝香(HHCB)、吐纳麝香(AHTN)和酮麝香(MK).相关性分析结果显示,HHCB、AHTN和MK可能有相近的来源和相似的环境行为.不同微环境中的SMs存在显著差异(P<0.05),家庭灰尘中∑SMs(49.6—1153 ng·g-1)含量要显著高于其他3种微环境.健康风险评估结果表明仅灰尘摄入这一暴露途径,SMs对成人和幼童所致健康风险有限.Abstract: From different micro-environments (including residential rooms, offices, chemical laboratories and instrumental rooms) in Guangzhou City, 45 indoor dust samples were collected and analyzed for the occurrence and distribution of 9 synthetic musks, then human health risk via indoor dust ingestion was assessed based on the measured concentrations. Total concentration of 9 synthetic musks (∑SMs) varied from 17.6 ng·g-1 to 1153 ng·g-1, being at low level worldwide. The 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-(g)2-benzopyrane was the dominant compound, followed by 7-acetyl-1,1,3,4,4,6-hexamethyl-tetraline and 4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone. Pearson correlation coefficients indicated their similar sources and environmental behavior. The concentrations of SMs in household indoor dust were significantly higher than those in other micro-environments (P<0.05). The Hazardous Index values of individual synthetic musk were far lower than 1, suggesting limited human health risk via dust ingestion.
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Key words:
- synthetic musks /
- indoor dust /
- Guangzhou city /
- human health risk
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