顶空-气相色谱法测定医用口罩和防护服中环氧乙烷和2-氯乙醇
Determination of ethylene oxide and 2-chloroethanol in medical masks and protective clothing by headspace-gas chromatography
-
摘要: 本文使用岛津HS-10顶空进样器结合GC-2010 Pro气相色谱仪，建立了顶空-气相色谱法测定医用口罩和防护服中环氧乙烷（EO）和2-氯乙醇（ECH）含量的方法.EO和ECH在配制标样浓度范围内标准曲线线性良好，相关系数在0.999以上，仪器检出限分别为0.012 μg·mL-1和0.13 μg·mL-1.以6针平行进样测试考察方法重复性，两个组分的峰面积RSD均小于5.0%.本方法可应用于医用口罩、防护服等医用防护用品中EO和ECH含量的快速定量测定.Abstract: A headspace-gas chromatography method was established by using Shimadzu HS-10 headspace sampler combined with GC-2010 Pro gas chromatograph, to determine ethylene oxide (EO) and 2-chloroethanol (ECH) in medical masks and protective clothing. The standard curve of EO and ECH was satisfied with the good correlation coefficient (r>0.999), and instrumental limit of detection are 0.012 μg·mL-1 and 0.13 μg·mL-1 for EO and ECH, respectively. The repeatability of the method was assessed with six parallel injection test. The peak area RSD of both components was less than 5.0%. The method was rapid, and successfully applied to determinate EO and ECH in medical protective equipment such as medical masks and protective clothing.
-
Key words:
- gas chromatography /
- headspace /
- ethylene oxide /
- 2-chloroehtanol /
- medical mask
-
-
[1] 张霞, 周雯, 王有森. 环氧乙烷在灭菌物品中残留量测定及毒性研究进展[J]. 中国消毒学杂志, 2005, 22(2):217-218. ZHANG X, ZHOU W, WANG Y S. Advances in the determination of residues and toxicity studies in sterilized articles[J]. China Journal of Disinfection, 2005, 22(2):217-218(in Chinese).
[2] 林红赛, 黄永富, 岳卫华等. 顶空气相色谱法同时测定一次性医疗器械产品中的环氧乙烷和2-氯乙醇[J]. 首都食品与医药, 2014, 22:102-104. LIN H S, HUANG Y F, YUE W H, et al. Determination of EO and ECH residuals in disposable medical device by headspace-gas chromatography[J]. Capital Medicine, 2014 , 22102-104(in Chinese).
-
点击查看大图
计量
- 文章访问数: 5050
- HTML全文浏览数: 5050
- PDF下载数: 178
- 施引文献: 0
下载:
