人尿中1-羟基芘与空气中多环芳烃的定量关系
STUDIES ON QUANTITATIVE RELATIONSHIP BETWEEN 1-HYDROXYPYRENE IN URINE AND CONTENT OF AMBIENT POLYNUCLEAR AROMATIC HYDROCARBONS
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摘要: 本文对不同采样点人尿中的1-羟基芘含量和受试人携带的个体空气采样器中以及所在环境中固定采样器中多环芳烃的浓度进行了测定。数理统计结果表明,尿中1-羟基芘与个体采样器中的芘或苯并(a)芘有显著的正相关。个体采样器的测定结果较客观地反映了受试人吸入空气中多环芳烃的浓度,证明尿中1-羟基芘在人体接触多环芳烃的健康风险评价中,是一个有效的生物监测指标。Abstract: The relation of 1-hydroxypyrene in urine with ambient PAHs was investigated with several groups of volunteers carrying personal air samplers and stationary samplers. The results demonstrate that 1-hydroxypyrene in human urine is correlated at a high level of significance with the contents of pyrene and benzo(a)pyrene in ambient air. It is suggested that 1-hydroxypyrene in human urine can be an effective biological monitoring index for assessment of health risk of human exposure to PAHs.
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Key words:
- urine /
- 1-hydroxypyrene /
- pyrene /
- benzo(a)pyrene
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