2021 Volume 40 Issue 2
Article Contents

WU Yuli, XIAO Yutang, WANG Guanping, SHI Wei, SUN Linquan, CHEN Yanfang, LI Dan. Research progress on status of environmental pollutions of polybrominated diphenyl ethers, hexabromocyclodocane, and tetrabromobisphenol A: A review[J]. Environmental Chemistry, 2021, (2): 384-403. doi: 10.7524/j.issn.0254-6108.2020050502
Citation: WU Yuli, XIAO Yutang, WANG Guanping, SHI Wei, SUN Linquan, CHEN Yanfang, LI Dan. Research progress on status of environmental pollutions of polybrominated diphenyl ethers, hexabromocyclodocane, and tetrabromobisphenol A: A review[J]. Environmental Chemistry, 2021, (2): 384-403. doi: 10.7524/j.issn.0254-6108.2020050502

Research progress on status of environmental pollutions of polybrominated diphenyl ethers, hexabromocyclodocane, and tetrabromobisphenol A: A review

  • Corresponding author: XIAO Yutang, 171220842@qq.com
  • Received Date: 05/05/2020
    Fund Project: Supported by Science and Technology Project of Guangdong Province (2013B020600006), Special Fund for Introducing Talents in Colleges and Universities of Guangdong Province(Guangdong Finance Education C1067501) and Special Fund for Shenzhen Strategic Emerging Industries Development(JSGG20170823153043998).
  • Polybrominated diphenyl ethers (PBDEs), hexabromocyclododecane (HBCD), and tetrabromobisphenol A (TBBPA) are the main traditional brominated flame retardants (BFRs). Owing to the property of Semi-volatility, persistance, and mobility, they are all found in various environmental media and organisms all over the world. Toxicological studies have shown that PBDEs, HBCD, and TBBPA not only exhibited obvious biological toxicity and carcinogenicity, but also posed potential harm to the ecological environment and human. This paper briefly summarized the current status of PBDEs, HBCD, and TBBPA in the environment, and discussed the level, distribution, exposure routes and toxicity of three traditional BFRs in non-living organisms (dust, water, soil, sediment, sludge) and living organisms (plants, animals, and humans). In addition, the problems existing in nowadays research were mentioned. Finally, a preliminary outlook for future research on PBDEs, HBCD, and TBBPA was presented.
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  • [1] UNEP. The new POPs under the Stockholm convention. Available. http://chm.pops.int/TheConvention/ThePOPs/TheNewPOPs/tabid/2511/Default.aspx[Z]. 2018.

    Google Scholar Pub Med

    [2] HERAT S. Environmental impacts and use of brominated flame retardants in electrical and electronic equipment[J]. Environmentalist, 2008, 28(4):348-357.

    Google Scholar Pub Med

    [3] EPA U. Brominated flame retardants|Science Inventory|US EPA. https://cfpub.epa.gov/si/si_public_record_report.cfm?Lab=NHEERL&dirEntryId=226582.[Z]. 2012.

    Google Scholar Pub Med

    [4] HARRAD S, DRAGE D S, SHARKEY M, et al. Perfluoroalkyl substances and brominated flame retardants in landfill-related air, soil, and groundwater from Ireland[J]. Science of the Total Environment, 2020, 705:135834.

    Google Scholar Pub Med

    [5] BARGHI M, SHIN E, KIM J, et al. Human exposure to HBCD and TBBPA via indoor dust in Korea:Estimation of external exposure and body burden[J]. Science of the Total Environment, 2017, 593/594:779-786.

    Google Scholar Pub Med

    [6] KADEMOGLOU K, XU F, PADILLA-SANCHEZ J A, et al. Legacy and alternative flame retardants in Norwegian and UK indoor environment:Implications of human exposure via dust ingestion[J]. Environment International, 2017, 102:48-56.

    Google Scholar Pub Med

    [7] CHOO G, LEE I, OH J. Species and habitat-dependent accumulation and biomagnification of brominated flame retardants and PBDE metabolites[J]. Journal of Hazardous Materials, 2019, 371:175-182.

    Google Scholar Pub Med

    [8] PEI J, YAO H, WANG H, et al. Polybrominated diphenyl ethers (PBDEs) in water, surface sediment, and suspended particulate matter from the Yellow River, China:Levels, spatial and seasonal distribution, and source contribution[J]. Marine Pollution Bulletin, 2018, 129:106-113.

    Google Scholar Pub Med

    [9] GUO J, ROMANAK K, WESTENBROEK S, et al. Current-use flame retardants in the water of lake michigan tributaries[J]. Environmental Science & Technology, 2017, 51(17):9960-9969.

    Google Scholar Pub Med

    [10] DREYER A, NEUGEBAUER F, LOHMANN N, et al. Recent findings of halogenated flame retardants (HFR) in the German and Polar environment[J]. Environmental Pollution, 2019, 253:850-863.

    Google Scholar Pub Med

    [11] ANIM A, DRAGE D, GOONETILLEKE A, et al. Distribution of PBDEs, HBCDs and PCBs in the Brisbane River estuary sediment[J]. Marine Pollution Bulletin, 2017, 120:165-173.

    Google Scholar Pub Med

    [12] SALAMOVA A, HITES R A. Brominated and chlorinated flame retardants in tree bark from around the globe[J]. Environmental Science & Technology, 2012, 47(1):349-354.

    Google Scholar Pub Med

    [13] POMA, GIULIA, MALYSHEVA, et al. Occurrence of selected halogenated flame retardants in Belgian foodstuff[J]. Chemosphere, 2018, 194:256-265.

    Google Scholar Pub Med

    [14] ANTIGNAC J P, MAIN K M, VIRTANEN H E, et al. Country-specific chemical signatures of persistent organic pollutants (POPs) in breast milk of French, Danish and Finnish women[J]. Environmental Pollution, 2016, 218:728-738.

    Google Scholar Pub Med

    [15] LIU L Y, HE K, HITES R A, et al. Hair and nails as noninvasive biomarkers of human exposure to brominated and organophosphate flame retardants[J]. Environmental Science & Technology, 2016, 50(6):3065-3073.

    Google Scholar Pub Med

    [16] DRAGE D S, HEFFERNAN A L, CUNNINGHAM T K, et al. Serum measures of hexabromocyclododecane (HBCDD) and polybrominated diphenyl ethers (PBDEs) in reproductive-aged women in the United Kingdom[J]. Environmental Research, 2019, 177:108631.

    Google Scholar Pub Med

    [17] JAKŠIĆ K, MATEK SARIĆ M, ČULIN J. Knowledge and attitudes regarding exposure to brominated flame retardants:A survey of Croatian health care providers[J]. Environmental Science & Pollution Research, 2020, 27(7):7683-7692.

    Google Scholar Pub Med

    [18] KACEW S, HAYES A W. Absence of neurotoxicity and lack of neurobehavioral consequences due to exposure to tetrabromobisphenol A (TBBPA) exposure in humans, animals and zebrafish[J]. Archives of Toxicology, 2020, 94(1):59-66.

    Google Scholar Pub Med

    [19] TOMY G T, PLESKACH K, FERGUSON S H, et al. Trophodynamics of some PFCs and BFRs in a western Canadian Arctic marine food web[J]. Environmental Science & Technology, 2009, 43(11):4076-4081.

    Google Scholar Pub Med

    [20] WANG Y W, CAI Y A. Research processes of persistent organic pollutants (POPs) newly listed and candidate POPs in Stockholm convention[J]. Scientia Sinica, 2010, 40(2):99-123.

    Google Scholar Pub Med

    [21] LU J F, HE M J, YANG Z H, et al. Occurrence of tetrabromobisphenol a (TBBPA) and hexabromocyclododecane (HBCD) in soil and road dust in Chongqing, western China, with emphasis on diastereoisomer profiles, particle size distribution, and human exposure[J]. Environmental Pollution, 2018, 242:219-228.

    Google Scholar Pub Med

    [22] de WIT C A, BJÖRKLUND J A, THURESSON K. Tri-decabrominated diphenyl ethers and hexabromocyclododecane in indoor air and dust from Stockholm microenvironments 2:Indoor sources and human exposure[J]. Environment International, 2012, 39(1):141-147.

    Google Scholar Pub Med

    [23] TUE N M, TAKAHASHI S, SUZUKI G, et al. Contamination of indoor dust and air by polychlorinated biphenyls and brominated flame retardants and relevance of non-dietary exposure in Vietnamese informal e-waste recycling sites[J]. Environment International, 2013, 51:160-167.

    Google Scholar Pub Med

    [24] CRISTALE J, BELÉ T G A, LACORTE S, et al. Occurrence of flame retardants in landfills:A case study in Brazil[J]. Environmental Research, 2018, 168:420-427.

    Google Scholar Pub Med

    [25] CHEN Y, LI J, TAN Q. Trends of production, consumption and environmental emissions of decabromodiphenyl ether in mainland China[J]. Environmental Pollution, 2020, 260:114022.

    Google Scholar Pub Med

    [26] LI W, LIU L, ZHANG Z, et al. Brominated flame retardants in the surrounding soil of two manufacturing plants in China:Occurrence, composition profiles and spatial distribution[J]. Environmental Pollution, 2016, 213:1-7.

    Google Scholar Pub Med

    [27] NI H, LU S, MO T, et al. Brominated flame retardant emissions from the open burning of five plastic wastes and implications for environmental exposure in China[J]. Environmental Pollution, 2016, 214:70-76.

    Google Scholar Pub Med

    [28] KUANG J, MA Y, HARRAD S. Concentrations of "legacy" and novel brominated flame retardants in matched samples of UK kitchen and living room/bedroom dust[J]. Chemosphere, 2016, 149:224-230.

    Google Scholar Pub Med

    [29] LEE H, KANG H, LEE S, et al. Human exposure to legacy and emerging flame retardants in indoor dust:A multiple-exposure assessment of PBDEs[J]. Science of the Total Environment, 2020, 719:137386.

    Google Scholar Pub Med

    [30] RAUERT C, SCHUSTER J K, ENG A, et al. Global atmospheric concentrations of brominated and chlorinated flame retardants and organophosphate esters[J]. Environmental Science & Technology, 2018, 52(5):2777-2789.

    Google Scholar Pub Med

    [31] MARTIN, BRITS, JAYNE, et al. Critical review of the analysis of brominated flame retardants and their environmental levels in Africa[J]. Chemosphere, 2016(164):174-189.

    Google Scholar Pub Med

    [32] CAO Z, YU G, CHEN Y, et al. Mechanisms influencing the BFR distribution patterns in office dust and implications for estimating human exposure[J]. Journal of Hazardous Materials, 2013, 252-253:11-18.

    Google Scholar Pub Med

    [33] CAO Z, XU F, LI W, et al. Seasonal and particle size-dependent variations of hexabromocyclododecanes in settled dust:Implications for sampling[J]. Environmental Science & Technology, 2015, 49(18):11151-11157.

    Google Scholar Pub Med

    [34] MOHAMED A E A, HARRAD S, IBARRA C, et al. Hexabromocyclododecanes in indoor dust from Canada, the United Kingdom, and the United States[J]. Environmental Science & Technology, 2008, 42(2):459-464.

    Google Scholar Pub Med

    [35] ZHU H, SUN H, YAO Y, et al. Legacy and alternative brominated flame retardants in outdoor dust and pine needles in mainland China:Spatial trends, dust-plant partitioning and human exposure[J]. Environmental Pollution, 2018, 243:758-765.

    Google Scholar Pub Med

    [36] ZHOU X, GUO J, ZHANG W, et al. Tetrabromobisphenol A contamination and emission in printed circuit board production and implications for human exposure[J]. Journal of Hazardous Materials, 2014, 273:27-35.

    Google Scholar Pub Med

    [37] CANADA E H. Screening assessment report:phenol, 4.4'-(1-methylethylidene) bis[2.6-dibromo-; Ethanol, 2,2'-[(1-methylethylidene)bis[(2,6-dibromo-4,1-phenylene)oxy]]bis; Benzene, 1.1'-(1-methylethylidene)bis[3.5-dibromo-4-(2-propenyloxy). Environment Canada, Health Canada. http://publications.gc.ca/pub?id=9.698608&sl=0[Z]. 2016.

    Google Scholar Pub Med

    [38] CHAIN E P O C. Scientific opinion on tetrabromobisphenol A (TBBPA) and its derivatives in food[J]. Efsa Journal, 2011, 9(12):2461-2477.

    Google Scholar Pub Med

    [39] NI H G, ZENG H. HBCD and TBBPA in particulate phase of indoor air in Shenzhen, China[J]. Science of the Total Environment, 2013, 458-460:15-19.

    Google Scholar Pub Med

    [40] MALKOSKE T, TANG Y, XU W, et al. A review of the environmental distribution, fate, and control of tetrabromobisphenol A released from sources[J]. Science of the Total Environment, 2016, 569/570:1608-1617.

    Google Scholar Pub Med

    [41] ABAFE O A, MARTINCIGH B S. Determination and human exposure assessment of polybrominated diphenyl ethers and tetrabromobisphenol A in indoor dust in South Africa[J]. Environmental Science & Pollution Research, 2016, 23(7):7038-7049.

    Google Scholar Pub Med

    [42] BRITS M, BRANDSMA S H, ROHWER E R, et al. Brominated and organophosphorus flame retardants in South African indoor dust and cat hair[J]. Environmental Pollution, 2019, 253:120-129.

    Google Scholar Pub Med

    [43] WU M, HAN T, XU G, et al. Occurrence of hexabromocyclododecane in soil and road dust from mixed-land-use areas of Shanghai, China, and its implications for human exposure[J]. Science of the Total Environment, 2016, 559:282-290.

    Google Scholar Pub Med

    [44] WANG W, ABUALNAJA K O, ASIMAKOPOULOS A G, et al. A comparative assessment of human exposure to tetrabromobisphenol A and eight bisphenols including bisphenol A via indoor dust ingestion in twelve countries[J]. Environment International, 2015, 83:183-191.

    Google Scholar Pub Med

    [45] JEON J, KIM C, KIM L, et al. Distribution and diastereoisomeric profiles of hexabromocyclododecanes in air, water, soil, and sediment samples in South Korea:Application of an optimized analytical method[J]. Ecotoxicology & Environmental Safety, 2019, 181:321-329.

    Google Scholar Pub Med

    [46] ROOSENS L, ABDALLAH M A, HARRAD S, et al. Exposure to hexabromocyclododecanes (HBCDs) via dust ingestion, but not diet, correlates with concentrations in human serum:Preliminary results[J]. Environmental Health Perspectives, 2009, 117(11):1707-1712.

    Google Scholar Pub Med

    [47] WEMKEN N, DRAGE D S, ABDALLAH M A, et al. Concentrations of brominated flame retardants in indoor air and dust from Ireland reveal elevated exposure to decabromodiphenyl ethane[J]. Environmental Science & Technology, 2019, 16(53):9826-9836.

    Google Scholar Pub Med

    [48] VENIER M, AUDY O E, VOJTA I, et al. Brominated flame retardants in the indoor environment-comparative study of indoor contamination from three countries[J]. Environment International, 2016, 94:150-160.

    Google Scholar Pub Med

    [49] TAO F, ABDALLAH A E, HARRAD S. Emerging and legacy flame retardants in UK indoor air and dust:Evidence for replacement of PBDEs by emerging flame retardants?[J]. Environmental Science & Technology, 2016, 50(23):13052-13061.

    Google Scholar Pub Med

    [50] ALI N, DIRTU A C, EEDE N V D, et al. Occurrence of alternative flame retardants in indoor dust from New Zealand:Indoor sources and human exposure assessment[J]. Chemosphere, 2012, 88(11):1276-1282.

    Google Scholar Pub Med

    [51] HARRAD S, ABDALLAH M A, NEIL L, et al. Current-use brominated flame retardants in water, sediment, and fish from English Lakes[J]. Environmental Science & Technology, 2009, 43(24):9077-9083.

    Google Scholar Pub Med

    [52] 李丹. 硫铁化物体系下典型卤代阻燃剂的非生物降解过程与机制[D]. 北京:中国科学院大学(中国科学院广州地球化学研究所),2017. LI D. Abiotic transformation of typical halogenated flame retardants by iron sulfides and sulfidated nanoscale zerovalent iron[D]. Beijing:University of Chinese Academy of Sciences(Guangzhou Institute of Geochemistry, Chinese Academy of Science), 2017(in Chinese).

    Google Scholar Pub Med

    [53] TRINH M M, TSAI C L, CHANG M B. Characterization of polybrominated diphenyl ethers (PBDEs) in various aqueous samples in Taiwan[J]. Science of the Total Environment, 2019, 649:388-395.

    Google Scholar Pub Med

    [54] CHOO G, KIM D H, KIM U J, et al. PBDEs and their structural analogues in marine environments:Fate and expected formation mechanisms compared with diverse environments[J]. Journal of Hazardous Materials, 2018, 343(5):116-124.

    Google Scholar Pub Med

    [55] GUSTAVSSON J, WIBERG K, NGUYEN M A, et al. Seasonal trends of legacy and alternative flame retardants in river water in a boreal catchment[J]. Science of the Total Environment, 2019, 692:1097-1105.

    Google Scholar Pub Med

    [56] GU S, EKPEGHERE K, KIM H, et al. Brominated flame retardants in marine environment focused on aquaculture area:Occurrence, source and bioaccumulation[J]. Science of the Total Environment, 2017, 601/602:1182-1191.

    Google Scholar Pub Med

    [57] 单慧媚,葛宁,肖骢. 多溴联苯醚在河套农灌区土壤和水体中的分布特征[J]. 环境科学与技术,2013,36(6):37-41. DAN H M, GE N, XIAO C. Distribution of PBDEs in soil and water from Hetao agriculture irrigation area[J]. Environmental Science & Technology, 2013, 36(6):37-41(in Chinese).

    Google Scholar Pub Med

    [58] LIANG X, JUNAID M, WANG Z, et al. Spatiotemporal distribution, source apportionment and ecological risk assessment of PBDEs and PAHs in the Guanlan River from rapidly urbanizing areas of Shenzhen, China[J]. Environmental Pollution, 2019, 250:695-707.

    Google Scholar Pub Med

    [59] SUTTON R, SEDLAK M D, YEE D, et al. Declines in polybrominated diphenyl ether contamination of San Francisco Bay following production phase-outs and bans[J]. Environmental Science & Technology, 2014, 49(2):777-784.

    Google Scholar Pub Med

    [60] SCHREDER E D, GUARDIA M J L. Flame retardant transfers from U.S. households (dust and laundry wastewater) to the aquatic environment[J]. Environmental Science & Technology, 2014, 48(19):11575-11583.

    Google Scholar Pub Med

    [61] 周鹏,于慧娟,赵建华,等. 典型污水处理厂中多溴联苯醚的分布特征、迁移及负荷研究[J]. 环境科学学报,2016,36(4):1248-1259. ZHOU P, YU H J, ZHAO J H, et al. The distribution, migration and mass loading of polybrominated diphenyl ether in a typical sewage treatment plant[J]. Acta Scientiae Circumstantiae, 2016, 36(4):1248-1259(in Chinese).

    Google Scholar Pub Med

    [62] CETIN B, ODABASI M. Air-water exchange and dry deposition of polybrominated diphenyl ethers at a coastal site in Izmir Bay, Turkey[J]. Environmental Science & Technology, 2007, 41:785-791.

    Google Scholar Pub Med

    [63] NYHOLM J R, GRABIC R, ARP H P H, et al. Environmental occurrence of emerging and legacy brominated flame retardants near suspected sources in Norway[J]. Science of the Total Environment, 2013, 443(15):307-314.

    Google Scholar Pub Med

    [64] COPETTI D M L V G. Intensive monitoring of conventional and surrogate quality parameters in a highly urbanized river affected by multiple combined sewer overflows[J]. Water Science & Technology:Water Supply, 2019, 3(19):953-966.

    Google Scholar Pub Med

    [65] ZHANG Y, LU Y, WANG P, et al. Transport of hexabromocyclododecane (HBCD) into the soil, water and sediment from a large producer in China[J]. Science of the Total Environment, 2018, 610/611:94-100.

    Google Scholar Pub Med

    [66] OH J, KOTANI K, MANAGAKI S, et al. Levels and distribution of hexabromocyclododecane and its lower brominated derivative in Japanese riverine environment[J]. Chemosphere, 2014, 109:157-163.

    Google Scholar Pub Med

    [67] CHOKWE T B, OKONKWO J O, SIBALI L L, et al. Alkylphenol ethoxylates and brominated flame retardants in water, fish (carp) and sediment samples from the Vaal River, South Africa[J]. Environmental Science & Pollution Research, 2015, 22(15):11922-11929.

    Google Scholar Pub Med

    [68] HU X, ANDREWS D, LINDSTROM A, et al. Detection of poly-and perfluoroalkyl substances (PFASs) in U.S. drinking water linked to industrial sites, military fire training areas, and wastewater treatment plants[J]. Environmental Science & Technology Letters, 2016, 3(10):344-350.

    Google Scholar Pub Med

    [69] KIM U, LEE I, OH J. Occurrence, removal and release characteristics of dissolved brominated flame retardants and their potential metabolites in various kinds of wastewater[J]. Environmental Pollution, 2016, 218:551-557.

    Google Scholar Pub Med

    [70] ICHIHARA M, YAMAMOTO A, TAKAKURA K I, et al. Distribution and pollutant load of hexabromocyclododecane (HBCD) in sewage treatment plants and water from Japanese rivers[J]. Chemosphere, 2014, 110:78-84.

    Google Scholar Pub Med

    [71] VENIER M, DOVE A, ROMANAK K, et al. Flame retardants and legacy chemicals in Great Lakes' water[J]. Environmental Science & Technology, 2014, 48(16):9563-9572.

    Google Scholar Pub Med

    [72] ROBSON M, MELYMUK L, BRADLEY L, et al. Wet deposition of brominated flame retardants to the Great Lakes basin-status and trends[J]. Environmental Pollution, 2013, 182:299-306.

    Google Scholar Pub Med

    [73] Hexabromocyclododecane Draft Risk Profile. UNEP/POPS/POPRC.6/Add.2; United Nations environment programme; Stockholm convention on persistent organic pollutants:Geneva, 2010[Z]. 2010.

    Google Scholar Pub Med

    [74] AGENCY U S E P. Partnership to evaluate flame retardant alternatives to HBCD:Publications[Z]. 2014.

    Google Scholar Pub Med

    [75] YANG C, ABDALLAH M A, DESBOROUGH J, et al. Trends in hexabromocyclododecanes in the UK and North America[J]. Science of the Total Environment, 2019, 658:861-867.

    Google Scholar Pub Med

    [76] EHC-172. Tetrabromobisphenol a and derivatives, international program on chemical safety. Geneva:World health organization. WHO/IPCS. Environmental health criteria 172:Tetrabromobisphenol A and derivatives. Geneva, world health organization[R]. 1995.

    Google Scholar Pub Med

    [77] DASO A P, ROHWER E R, KOOT D J. Preliminary screening of polybrominated diphenyl ethers (PBDEs), hexabromocyclododecane (HBCDD) and tetrabromobisphenol A (TBBPA) flame retardants in landfill leachate[J]. Environmental Monitoring & Assessment, 2017, 189(8):418.

    Google Scholar Pub Med

    [78] LAN J, SHEN Z, GAO W, et al. Occurrence of bisphenol-A and its brominated derivatives in tributary and estuary of Xiaoqing River adjacent to Bohai Sea, China[J]. Marine Pollution Bulletin, 2019, 149:110551.

    Google Scholar Pub Med

    [79] YANG S, WANG S, LIU H, et al. Tetrabromobisphenol A:Tissue distribution in fish, and seasonal variation in water and sediment of Lake Chaohu, China[J]. Environmental Science & Pollution Research, 2012, 19(9):4090-4096.

    Google Scholar Pub Med

    [80] GUSTAVSSON J, WIBERG K, RIBELI E, et al. Screening of organic flame retardants in Swedish river water[J]. Science of the Total Environment, 2018, 625:1046-1055.

    Google Scholar Pub Med

    [81] GONG W J, ZHU L Y, JIANG T T, et al. The occurrence and spatial-temporal distribution of tetrabromobisphenol A in the coastal intertidal zone of Qingdao in China, with a focus on toxicity assessment by biological monitoring[J]. Chemosphere, 2017, 185:462-467.

    Google Scholar Pub Med

    [82] XU J, ZHANG Y, GUO C, et al. Levels and distribution of tetrabromobisphenol A and hexabromocyclododecane in Taihu Lake, China[J]. Environmental Toxicology & Chemistry, 2013, 32(10):2249-2255.

    Google Scholar Pub Med

    [83] LIU K, LI J, YAN S, et al. A review of status of tetrabromobisphenol A (TBBPA) in China[J]. Chemosphere, 2016, 148:8-20.

    Google Scholar Pub Med

    [84] OROS D R, HOOVER D, RODIGARI F, et al. Levels and distribution of polybrominated diphenyl ethers in water, surface sediments, and bivalves from the San Francisco estuary[J]. Environmental Science & Technology, 2015, 39(1):33-41.

    Google Scholar Pub Med

    [85] LABADIE P, TLILI K, ALLIOT F, et al. Development of analytical procedures for trace-level determination of polybrominated diphenyl ethers and tetrabromobisphenol A in river water and sediment[J]. Analytical & Bioanalytical Chemistry, 2009, 396:865-875.

    Google Scholar Pub Med

    [86] VORKAMP K, BOSSI R, KAI B, et al. New priority substances of the European water framework directive:Biocides, pesticides and brominated flame retardants in the aquatic environment of Denmark[J]. Science of the Total Environment, 2014, 470/471(1):459-468.

    Google Scholar Pub Med

    [87] LARA A B, CABALLO C, SICILIA M D, et al. Halogen bonding for increasing efficiency in liquid-liquid microextraction:Application to the extraction of hexabromocyclododecane enantiomers in river water[J]. Journal of Chromatography A, 2019, 1600:95-104.

    Google Scholar Pub Med

    [88] CHOKWE T, OKONKWO O, SIBALI L, et al. Occurrence and distribution pattern of alkylphenol ethoxylates and brominated flame retardants in sediment samples from Vaal River, South Africa[J]. Bulletin of Environmental Contamination & Toxicology, 2016, 7(97):353-358.

    Google Scholar Pub Med

    [89] YUE C, LI L. Filling the gap:Estimating physicochemical properties of the full array of polybrominated diphenyl ethers (PBDEs)[J]. Environmental Pollution, 2013, 180:312-323.

    Google Scholar Pub Med

    [90] TOMY T, BUDAKOWSKI W, HALLDORSON T, et al. Biomagnification of α-and β-hexabromocyclododecane isomers in a Lake Ontario food web[J]. Environmental Science & Technology, 2004, 38(8):2298-2303.

    Google Scholar Pub Med

    [91] CHU S, HAFFNER G, LETCHER R. Simultaneous determination of tetrabromobisphenol A, tetrachlorobisphenol A, bisphenol A and other halogenated analogues in sediment and sludge by high performance liquid chromatography-electrospray tandem mass spectrometry[J]. Journal of Chromatography A, 2006, 1097:25-32.

    Google Scholar Pub Med

    [92] LI H, LA GUARDIA M J, LIU H, et al. Brominated and organophosphate flame retardants along a sediment transect encompassing the Guiyu, China e-waste recycling zone[J]. Science of the Total Environment, 2019, 646:58-67.

    Google Scholar Pub Med

    [93] LA GUARDIA M J, HALE R C, NEWMAN B. Brominated flame-retardants in Sub-Saharan Africa:Burdens in inland and coastal sediments in the eThekwini Metropolitan Municipality, South Africa[J]. Environmental Science & Technology, 2013, 47(17):9643-9650.

    Google Scholar Pub Med

    [94] LEE I, KANG H, KIM U, et al. Brominated flame retardants in Korean river sediments, including changes in polybrominated diphenyl ether concentrations between 2006 and 2009[J]. Chemosphere, 2015, 126C:18-24.

    Google Scholar Pub Med

    [95] MAN Y, CHOW K L, MAN M, et al. Profiles and removal efficiency of polybrominated diphenyl ethers by two different types of sewage treatment work in Hong Kong[J]. Science of the Total Environment, 2015, 505:261-268.

    Google Scholar Pub Med

    [96] LI B, SUN S, HUO C, et al. Occurrence and fate of PBDEs and novel brominated flame retardants in a wastewater treatment plant in Harbin, China[J]. Environmental Science & Pollution Research, 2016, 19(23):19246-19256.

    Google Scholar Pub Med

    [97] DEMIRTEPE H, IMAMOGLU I. Levels of polybrominated diphenyl ethers and hexabromocyclododecane in treatment plant sludge:Implications on sludge management[J]. Chemosphere, 2019, 221:606-615.

    Google Scholar Pub Med

    [98] De la TORRE A, ALONSO E, CONCEJERO M A, et al. Sources and behaviour of polybrominated diphenyl ethers (PBDEs), polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in Spanish sewage sludge[J]. Waste Management, 2011, 31(6):1277-1284.

    Google Scholar Pub Med

    [99] ZHANG Z, SUN Y, SUN K, et al. Brominated flame retardants in mangrove sediments of the Pearl River estuary, South China:Spatial distribution, temporal trend and mass inventory[J]. Chemosphere, 2015, 123:26-32.

    Google Scholar Pub Med

    [100] RICHMAN L A, KOLIC T, MACPHERSON K, et al. Polybrominated diphenyl ethers in sediment and caged mussels (elliptio complanata) deployed in the Niagara River[J]. Chemosphere, 2013, 92(7):778-786.

    Google Scholar Pub Med

    [101] BARÓN E, GAGO-FERRERO P, GORGA M, et al. Occurrence of hydrophobic organic pollutants (BFRs and UV-filters) in sediments from South America[J]. Chemosphere, 2013, 92(3):309-316.

    Google Scholar Pub Med

    [102] HAUKÅS M, HYLLAND K, BERGE J A, et al. Spatial diastereomer patterns of hexabromocyclododecane (HBCD) in a Norwegian fjord[J]. Science of the Total Environment, 2009, 407(22):5907-5913.

    Google Scholar Pub Med

    [103] GAO C, XIA L, WU C, et al. The effects of prosperity indices and land use indicators of an urban conurbation on the occurrence of hexabromocyclododecanes and tetrabromobisphenol A in surface soil in South China[J]. Environmental Pollution, 2019, 252:1810-1818.

    Google Scholar Pub Med

    [104] FENG A, CHEN S, CHEN M, et al. Hexabromocyclododecane (HBCD) and tetrabromobisphenol A (TBBPA) in riverine and estuarine sediments of the Pearl River Delta in southern China, with emphasis on spatial variability in diastereoisomer-and enantiomer-specific distribution of HBCD[J]. Marine Pollution Bulletin, 2012, 64(5):919-925.

    Google Scholar Pub Med

    [105] KAJIWARA N, TAKIGAMI H. Emission behavior of hexabromocyclododecanes and polybrominated diphenyl ethers from flame-retardant-treated textiles[J]. Environmental Science:Processes & Impacts, 2013, 15(10):1957-1963.

    Google Scholar Pub Med

    [106] GORGA M, MARTÍNEZ E, GINEBREDA A, et al. Determination of PBDEs, HBB, PBEB, DBDPE, HBCD, TBBPA and related compounds in sewage sludge from Catalonia (Spain)[J]. Science of the Total Environment, 2013, 444:51-59.

    Google Scholar Pub Med

    [107] GANCI A P, VANE C H, ABDALLAH M A E, et al. Legacy PBDEs and NBFRs in sediments of the tidal River Thames using liquid chromatography coupled to a high resolution accurate mass orbitrap mass spectrometer[J]. Science of the Total Environment, 2019, 658:1355-1366.

    Google Scholar Pub Med

    [108] CHENG H, WANG Y, ZHU T, et al. Effects of hydrodynamic disturbances on biodegradation of tetrabromobisphenol A in water-sediment systems[J]. Environmental Science & Pollution Research, 2019, 26(30):31392-31400.

    Google Scholar Pub Med

    [109] MCAVOY D C, PITTINGER C A, WILLIS A M. Biotransformation of tetrabromobisphenol A (TBBPA) in anaerobic digester sludge, soils, and freshwater sediments[J]. Ecotoxicology & Environmental Safety, 2016, 131:143-150.

    Google Scholar Pub Med

    [110] MATSUKAMI H, TUE N M, SUZUKI G, et al. Flame retardant emission from e-waste recycling operation in northern Vietnam:Environmental occurrence of emerging organophosphorus esters used as alternatives for PBDEs[J]. Science of the Total Environment, 2015, 514:492-499.

    Google Scholar Pub Med

    [111] WANG J, LIU L, WANG J, et al. Distribution of metals and brominated flame retardants (BFRs) in sediments, soils and plants from an informal e-waste dismantling site, South China[J]. Environmental Science & Pollution Research, 2015, 22(2):1020-1033.

    Google Scholar Pub Med

    [112] ROTHENBACHER K P, PECQUET A M. Summary of historical terrestrial toxicity data for the brominated flame retardant tetrabromobisphenol A (TBBPA):Effects on soil microorganisms, earthworms, and seedling emergence[J]. Environmental Science & Pollution Research, 2018, 25(18):17268-17277.

    Google Scholar Pub Med

    [113] 王俊霞,刘莉莉,郭杰,等. 溴代阻燃剂在中国川藏地区的污染和分布特征[J]. 环境科学学报,2014,34(11):2823-2831. WANG J X, LIU L L, GUO J, et al. Levels and distribution of brominated flame retardants in Sichuan-Tibet region, China[J]. Acta Scientiae Circumstantiae. 2014, 34(11):2823-2831(in Chinese).

    Google Scholar Pub Med

    [114] LEE H J, KIM G B. Removal rate and releases of polybrominated diphenyl ethers in two wastewater treatment plants, Korea[J]. Ocean Science Journal, 2017, 52(2):193-205.

    Google Scholar Pub Med

    [115] KOTTHOFF M, RVDEL H, JVRLING H. Detection of tetrabromobisphenol A and its mono-and dimethyl derivatives in fish, sediment and suspended particulate matter from European freshwaters and estuaries[J]. Analytical & Bioanalytical Chemistry, 2017, 409(14):3685-3694.

    Google Scholar Pub Med

    [116] LI F, JIN J, TAN D, et al. Hexabromocyclododecane and tetrabromobisphenol A in sediments and paddy soils from Liaohe River Basin, China:Levels, distribution and mass inventory[J]. Journal of Environmental Sciences, 2016, 48:209-217.

    Google Scholar Pub Med

    [117] PAROLINI M, GUAZZONI N, COMOLLI R, et al. Background levels of polybrominated diphenyl ethers (PBDEs) in soils from Mount Meru area, Arusha district (Tanzania)[J]. Science of the Total Environment, 2013, 452/453:253-261.

    Google Scholar Pub Med

    [118] SÁNCHEZ-BRUNETE C, MIGUEL E, TADEO J L. Determination of tetrabromobisphenol-A, tetrachlorobisphenol-A and bisphenol-A in soil by ultrasonic assisted extraction and gas chromatography-mass spectrometry[J]. Journal of Chromatography A, 2009, 1216(29):5497-5503.

    Google Scholar Pub Med

    [119] CAMPO J, LORENZO M, CAMMERAAT E L H, et al. Emerging contaminants related to the occurrence of forest fires in the Spanish Mediterranean[J]. Science of the Total Environment, 2017, 603/604:330-339.

    Google Scholar Pub Med

    [120] KLOSTERHAUS S L, STAPLETON H M, La GUARDIA M J, et al. Brominated and chlorinated flame retardants in San Francisco Bay sediments and wildlife[J]. Environment International, 2012, 47:56-65.

    Google Scholar Pub Med

    [121] HAJDUK A, BOJANOWICZ-BABLOK A. Polybrominated diphenyl ethers as the emerging contaminants in the Polish environment[J]. Rocznik Ochrona Srodowiska, 2019, 21:395-420.

    Google Scholar Pub Med

    [122] SONG S, SONG M, ZENG L, et al. Occurrence and profiles of bisphenol analogues in municipal sewage sludge in China[J]. Environmental Pollution, 2014, 186:14-19.

    Google Scholar Pub Med

    [123] HUANG H, WANG D, WAN W, et al. Hexabromocyclododecanes in soils and plants from a plastic waste treatment area in North China:Occurrence, diastereomer-and enantiomer-specific profiles, and metabolization[J]. Environmental Science & Pollution Research, 2017, 24(27):21625-21635.

    Google Scholar Pub Med

    [124] LI H, HU Y, SUN Y, et al. Bioaccumulation and translocation of tetrabromobisphenol A and hexabromocyclododecanes in mangrove plants from a national nature reserve of Shenzhen City, South China[J]. Environment International, 2019, 129:239-246.

    Google Scholar Pub Med

    [125] ZHU C, WANG P, LI Y, et al. Trophic transfer of hexabromocyclododecane in the terrestrial and aquatic food webs from an e-waste dismantling region in East China.[J]. Environmental Science Processes & Impacts, 2017(2):154-160.

    Google Scholar Pub Med

    [126] CORSOLINI S, ADEMOLLO N, MARTELLINI T, et al. Legacy persistent organic pollutants including PBDEs in the trophic web of the Ross Sea (Antarctica)[J]. Chemosphere, 2017, 185:699-708.

    Google Scholar Pub Med

    [127] REINDL A R, FALKOWSKA L. Flame retardants at the top of a simulated baltic marine food web-a case study concerning African penguins from the Gdansk Zoo[J]. Archives of Environmental Contamination & Toxicology, 2015, 68(2):259-264.

    Google Scholar Pub Med

    [128] GAO M, WANG G, LIN B, et al. Study on arbor leaf and ring as a potential biological indicator for atmospheric polybrominated diphenyl ethers (PBDEs) distribution at e-wastes recycling sites[J]. International Journal of Environmental Science & Technology, 2019, 16(12):8639-8652.

    Google Scholar Pub Med

    [129] RAUERT C, HARNER T. A preliminary investigation into the use of red pine (pinus resinosa) tree cores as historic passive samplers of POPs in outdoor air[J]. Atmospheric Environment, 2016, 140:514-518.

    Google Scholar Pub Med

    [130] CHROPEŇOVÁ M, GREGUŠKOVÁ E K, KARÁSKOVÁ P, et al. Pine needles and pollen grains of pinus mugo turra-a biomonitoring tool in high mountain habitats identifying environmental contamination[J]. Ecological Indicators, 2016, 66:132-142.

    Google Scholar Pub Med

    [131] DREYER A, NICKEL S, SCHRÖDER W. (Persistent) organic pollutants in Germany:Results from a pilot study within the 2015 moss survey[J]. Environmental Sciences Europe, 2018, 30(1):43.

    Google Scholar Pub Med

    [132] MORRIS A D, MUIR D C G, SOLOMON K R, et al. Bioaccumulation of polybrominated diphenyl ethers and alternative halogenated flame retardants in a vegetation-caribou-wolf food chain of the Canadian Arctic[J]. Environmental Science & Technology, 2018, 52(5):3136-3145.

    Google Scholar Pub Med

    [133] KIM J, CHOI Y, BARGHI M, et al. Occurrence and distribution of old and new halogenated flame retardants in mosses and lichens from the South Shetland Islands, Antarctica[J]. Environmental Pollution, 2018, 235:302-311.

    Google Scholar Pub Med

    [134] MA X, WANG Z, YU L, et al. Mirror image between gas-particle partitioning and soil-moss distribution of polybrominated diphenyl ethers in the Polar regions[J]. Science of the Total Environment, 2019, 656:1199-1206.

    Google Scholar Pub Med

    [135] QIU Y, QIU H, ZHANG G, et al. Bioaccumulation and cycling of polybrominated diphenyl ethers (PBDEs) and dechlorane plus (DP) in three natural mangrove ecosystems of South China[J]. Science of the Total Environment, 2019, 651:1788-1795.

    Google Scholar Pub Med

    [136] CHAI M, LI R, SHI C, et al. Contamination of polybrominated diphenyl ethers (PBDEs) in urban mangroves of southern China[J]. Science of the Total Environment, 2019, 646:390-399.

    Google Scholar Pub Med

    [137] SALAMOVA A, HITES R A. Evaluation of tree bark as a passive atmospheric sampler for flame retardants, PCBs, and organochlorine pesticides[J]. Environmental Science & Technology, 2010, 44(16):6196-6201.

    Google Scholar Pub Med

    [138] ALI N, MALIK R N, MEHDI T, et al. Organohalogenated contaminants (OHCs) in the serum and hair of pet cats and dogs:Biosentinels of indoor pollution[J]. Science of the Total Environment, 2013, 449:29-36.

    Google Scholar Pub Med

    [139] CHOW K, HEARN L K, ZUBER M, et al. Evaluation of polybrominated diphenyl ethers (PBDEs) in matched cat sera and house dust samples:Investigation of a potential link between PBDEs and spontaneous feline hyperthyroidism[J]. Environmental Research, 2015, 136:173-179.

    Google Scholar Pub Med

    [140] GUO W, PARK J, WANG Y, et al. High polybrominated diphenyl ether levels in California house cats:House dust a primary source?[J]. Environmental Toxicology & Chemistry, 2012, 31(2):301-306.

    Google Scholar Pub Med

    [141] VETTER W, GALLISTL C, SCHLIENZ A, et al. Brominated flame retardants (BFRs) in eggs from birds of prey from southern Germany, 2014[J]. Environmental Pollution, 2017, 231:569-577.

    Google Scholar Pub Med

    [142] EULAERS I, JASPERS V L B, PINXTEN R, et al. Legacy and current-use brominated flame retardants in the barn owl[J]. Science of the Total Environment, 2014, 472:454-462.

    Google Scholar Pub Med

    [143] SU G, LETCHER R J, MOORE J N, et al. Contaminants of emerging concern in caspian tern compared to herring gull eggs from michigan colonies in the Great Lakes of North America[J]. Environmental Pollution, 2017, 222:154-164.

    Google Scholar Pub Med

    [144] CHEN F, ZENG S, MA J, et al. Interactions between decabromodiphenyl ether and lead in soil-plant system[J]. Chemosphere, 2019, 236:124406.

    Google Scholar Pub Med

    [145] LI H, HUANG W X, GAO M Y, et al. AM fungi increase uptake of Cd and BDE-209 and activities of dismutase and catalase in amaranth (amaranthus hypochondriacus L.) in two contaminants spiked soil[J]. Ecotoxicology & Environmental Safety, 2020, 195:110485.

    Google Scholar Pub Med

    [146] 孟雨婷,张卫荣,汪娟,等. 多溴联苯醚的植物毒理学研究进展[J]. 植物生理学报,2018,54(2):183-191. MENG Y T, ZHANG W R, WANG J, et al. Research progress of plant toxicology of polybrominated diphenyl ethers (PBDEs)[J]. Research progress of plant toxicology of polybrominated diphenyl ethers (PBDEs), 2018, 54(2):183-191(in Chinese).

    Google Scholar Pub Med

    [147] SUN Y, WANG C, XU X, et al. Responses of plants to polybrominated diphenyl ethers (PBDEs) induced phytotoxicity:A hierarchical meta-analysis[J]. Chemosphere, 2020, 240:124865.

    Google Scholar Pub Med

    [148] HE H, SHI X, LAWRENCE A, et al. 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) induces wide metabolic changes including attenuated mitochondrial function and enhanced glycolysis in PC12 cells[J]. Ecotoxicology & Environmental Safety, 2020, 201:110849.

    Google Scholar Pub Med

    [149] 王先锋. 多溴联苯醚(PBDEs)和铅(Pb)对斑马鱼的神经毒性和内分泌干扰效应[D]. 北京:中国科学院大学,2016. WANG X F. 2016. Neurotoxicity and endocrine disruption effects of polybrominated diphenyl ethers (PBDEs) and lead (Pb) on zebrafish[D]. Beijing:University of Chinese Academy of Sciences, 2016(in Chinese).

    Google Scholar Pub Med

    [150] HAN T, WU M, ZANG C, et al. Hexabromocyclododecane and tetrabromobisphenol A in tree bark from different functional areas of Shanghai, China:Levels and spatial distributions[J]. Environmental Science:Processes Impacts, 2017, 19(10):1346-1354.

    Google Scholar Pub Med

    [151] ZHU H, ZHANG K, SUN H, et al. Spatial and temporal distributions of hexabromocyclododecanes in the vicinity of an expanded polystyrene material manufacturing plant in Tianjin, China[J]. Environmental Pollution, 2017, 222:338-347.

    Google Scholar Pub Med

    [152] WALTERS D M, JARDINE T D, CADE B S, et al. Trophic magnification of organic chemicals:A global synthesis[J]. Environmental Science & Technology, 2016, 50(9):4650-4658.

    Google Scholar Pub Med

    [153] 朱娜丽. 青藏高原等地区持久性有机污染物和新型污染物的环境行为研究[D]. 北京:中国科学院研究生院,2013. ZHU L N. Environmental behaviors of persistent organic pollutants and emerging contaminants in the Tibetan Plateau[D]. Beijing:KMS of Research Center for Eco-Environmental Sciences, 2013(in Chinese).

    Google Scholar Pub Med

    [154] ZHANG H, KELLY B C. Sorption and bioaccumulation behavior of multi-class hydrophobic organic contaminants in a tropical marine food web[J]. Chemosphere, 2018, 199:44-53.

    Google Scholar Pub Med

    [155] WANG W, CHOO G, CHO H, et al. The occurrence and distribution of hexabromocyclododecanes in freshwater systems, focusing on tissue-specific bioaccumulation in crucian carp[J]. Science of the Total Environment, 2018, 635:470-478.

    Google Scholar Pub Med

    [156] ZHANG Y, SUN H, LIU F, et al. Hexabromocyclododecanes in limnic and marine organisms and terrestrial plants from Tianjin, China:Diastereomer-and enantiomer-specific profiles, biomagnification, and human exposure[J]. Chemosphere, 2013, 93(8):1561-1568.

    Google Scholar Pub Med

    [157] 武彤,张淑贞. 六溴环十二烷非对映体的植物吸收和毒性效应[C]. 中国化学会学术年会,2012. WU T, ZHANG S Z. Plant absorption and toxic effects of HBCD diastereomers[C]. Academic Annual Conference of Chinese Chemical Society, 2012(in Chinese).

    Google Scholar Pub Med

    [158] 周耀红,马晓净,吕辉雄. 六溴环十二烷对土壤酶活性、种子发芽率及根伸长的影响[J]. 环境化学,2017,36(1):100-105. ZHOU Y H, MA X J, LU H X. Effect of hexabromocyclododecane (HBCDs) on soil enzyme activity, seed germination rate and root elongation[J]. Environmental Chemistry, 2017, 36(1):100-105(in Chinese).

    Google Scholar Pub Med

    [159] 耿金瑶,王莹莹. 六溴环十二烷异构体的毒理效应及其在生物体内的代谢转化过程研究进展[J]. 环境化学,2017,36(12):40-48. GENG J Y, WANG Y Y. Toxicological effects and metabolic transformation of hexabromocyclododecane isomers in organisms:A review[J]. Environmental Chemistry, 2017, 36(12):40-48(in Chinese).

    Google Scholar Pub Med

    [160] BERTUCCI J I, MALALA IRUGAL BANDARALAGE S, HECKER M. Assessing the cytotoxic effect of hexabromocyclododecane (HBCD) on liver tissue cultures from fathead minnow (pimephales promelas)[J]. Aquatic Toxicology, 2020, 225:105523.

    Google Scholar Pub Med

    [161] 陆雅婕,吴笛,尹颖,等. 重金属和溴代阻燃剂复合污染对小白菜的生物效应[J]. 南京大学学报(自然科学),2018,54(1):196-204. LU Y J, WU D, YIN Y, et al. Combined efefect of heavy metalals and bromine flame retardants for pakchoi[J]. Journal of Nanjing University (Natural Science), 2018, 54(1):196-204(in Chinese).

    Google Scholar Pub Med

    [162] 邓结平. TBBPA对海洋微藻毒性效应的研究[D]. 青岛:中国海洋大学,2014. DENG J P. Toxic effect of TBBPA on marine microalgae[D]. Qingdao:Ocean University of China, 2014(in Chinese).

    Google Scholar Pub Med

    [163] LIU A, QU G, YU M, et al. Tetrabromobisphenol-A/S and nine novel analogs in biological samples from the Chinese Bohai Sea:Implications for trophic transfer[J]. Environmental Science & Technology, 2016, 50(8):4203-4211.

    Google Scholar Pub Med

    [164] LIU X, ZHANG X, ZHANG K, et al. Sodium persulfate-assisted mechanochemical degradation of tetrabromobisphenol A:Efficacy, products and pathway[J]. Chemosphere, 2016, 150:551-558.

    Google Scholar Pub Med

    [165] YU Y, YU Z, CHEN H, et al. Tetrabromobisphenol A:Disposition, kinetics and toxicity in animals and humans[J]. Environmental Pollution, 2019, 253:909-917.

    Google Scholar Pub Med

    [166] ROCK K D, GILLERA S E A, DEVARASETTY P, et al. Sex-specific behavioral effects following developmental exposure to tetrabromobisphenol A (TBBPA) in Wistar rats[J]. NeuroToxicology, 2019, 75:136-147.

    Google Scholar Pub Med

    [167] CHEN X, GU J, WANG Y, et al. Fate and o-methylating detoxification of tetrabromobisphenol A (TBBPA) in two earthworms (metaphire guillelmi and eisenia fetida)[J]. Environmental Pollution, 2017, 227:526-533.

    Google Scholar Pub Med

    [168] PITTINGER C A, PECQUET A M. Review of historical aquatic toxicity and bioconcentration data for the brominated flame retardant tetrabromobisphenol A (TBBPA):effects to fish, invertebrates, algae, and microbial communities[J]. Environmental Science & Pollution Research, 2018, 25(15):14361-14372.

    Google Scholar Pub Med

    [169] HE C, JIN J, WANG Y, et al. Polybrominated diphenyl ethers, dechlorane plus, and polychlorinated biphenyls in tree bark near the upper Yellow River, China[J]. Environmental Toxicology & Chemistry, 2014, 33(8):1732-1738.

    Google Scholar Pub Med

    [170] MA X, ZHANG H, YAO W, et al. Occurrence and bioaccumulation of polybrominated diphenyl ethers in sediments and paddy ecosystems of Liaohe River basin, northeast China[J]. Journal of Environmental Sciences, 2016, 43:250-256.

    Google Scholar Pub Med

    [171] SHI Z, ZHANG L, ZHAO Y, et al. Dietary exposure assessment of Chinese population to tetrabromobisphenol-A, hexabromocyclododecane and decabrominated diphenyl ether:Results of the 5th Chinese total diet study[J]. Environmental Pollution, 2017, 229:539-547.

    Google Scholar Pub Med

    [172] POMA G, VOLTA P, ROSCIOLI C, et al. Concentrations and trophic interactions of novel brominated flame retardants, HBCD, and PBDEs in zooplankton and fish from Lake Maggiore (northern Italy)[J]. Science of the Total Environment, 2014, 481:401-408.

    Google Scholar Pub Med

    [173] MORRIS S, ALLCHIN C R, ZEGERS B N, et al. Distribution and fate of HBCD and TBBPA brominated flame retardants in North Sea Estuaries and aquatic food webs[J]. Environmental Science & Technology, 2004, 38(21):5497-5504.

    Google Scholar Pub Med

    [174] PARDO O, BESER M I, YUSÀ V, et al. Probabilistic risk assessment of the exposure to polybrominated diphenyl ethers via fish and seafood consumption in the region of Valencia (Spain)[J]. Chemosphere, 2014, 104:7-14.

    Google Scholar Pub Med

    [175] RVDEL H, MVLLER J, NOWAK J, et al. Hexabromocyclododecane diastereomers in fish and suspended particulate matter from selected European waters-trend monitoring and environmental quality standard compliance[J]. Environmental Science & Pollution Research, 2017, 24(22):18048-18062.

    Google Scholar Pub Med

    [176] SVIHLIKOVA V, LANKOVA D, POUSTKA J, et al. Perfluoroalkyl substances (PFASs) and other halogenated compounds in fish from the upper Labe River basin[J]. Chemosphere, 2015, 129:170-178.

    Google Scholar Pub Med

    [177] FUJⅡ Y, KATO Y, MASUDA N, et al. Contamination trends and factors affecting the transfer of hexabromocyclododecane diastereomers, tetrabromobisphenol A, and 2,4,6-tribromophenol to breast milk in Japan[J]. Environmental Pollution, 2018, 237:936-943.

    Google Scholar Pub Med

    [178] YIN L, SIRACUSA J S, MEASEL E, et al. High-content image-based single-cell phenotypic analysis for the testicular toxicity prediction induced by bisphenol A and its analogs bisphenol S, bisphenol AF, and tetrabromobisphenol A in a three-dimensional testicular cell co-culture model[J]. Toxicological Sciences, 2019, 173(2):313-335.

    Google Scholar Pub Med

    [179] GAYLORD A, OSBORNE G, GHASSABIAN A, et al. Trends in neurodevelopmental disability burden due to early life chemical exposure in the USA from 2001 to 2016:A population-based disease burden and cost analysis[J]. Molecular & Cellular Endocrinology, 2020, 502:110666.

    Google Scholar Pub Med

    [180] PARK C, KIM S, LEE W K, et al. Tetrabromobisphenol-A induces apoptotic death of auditory cells and hearing loss[J]. Biochemical & Biophysical Research Communications, 2016, 478(4):1667-1673.

    Google Scholar Pub Med

    [181] SUN M, LI X, XU Y, et al. Exposure to PBDE47 affects mouse oocyte quality via mitochondria dysfunction-induced oxidative stress and apoptosis[J]. Ecotoxicology & Environmental Safety, 2020, 198:110662.

    Google Scholar Pub Med

    [182] ZHU M, NIU Y, LI Y, et al. Low concentrations of tetrabromobisphenol A disrupt notch signaling and intestinal development in in vitro and in vivo models[J]. Chemical Research in Toxicology, 2020, 33(6):1418-1427.

    Google Scholar Pub Med

    [183] KIM J, KANG J, CHOI S, et al. Levels of polybrominated diphenyl ethers in the Korean metropolitan population are declining:A trend from 2001 to 2013[J]. Environmental Toxicology & Chemistry, 2018, 37(9):2323-2330.

    Google Scholar Pub Med

    [184] BUTTKE D E, WOLKIN A, STAPLETON H M, et al. Associations between serum levels of polybrominated diphenyl ether (PBDE) flame retardants and environmental and behavioral factors in pregnant women[J]. Journal of Exposure Science & Environmental Epidemiology, 2013, 23(2):176-182.

    Google Scholar Pub Med

    [185] QIAO L, ZHENG X, YAN X, et al. Brominated flame retardant (BFRs) and dechlorane Plus (DP) in paired human serum and segmented hair[J]. Ecotoxicology & Environmental Safety, 2018, 147:803-808.

    Google Scholar Pub Med

    [186] TAO F, ABOU-ELWAFA ABDALLAH M, ASHWORTH D C, et al. Emerging and legacy flame retardants in UK human milk and food suggest slow response to restrictions on use of PBDEs and HBCDD[J]. Environment International, 2017, 105:95-104.

    Google Scholar Pub Med

    [187] HUANG M, LI J, XIAO Z, et al. Tetrabromobisphenol A and hexabromocyclododecane isomers in breast milk from the general population in Beijing, China:Contamination levels, temporal trends, nursing infant's daily intake, and risk assessment[J]. Chemosphere, 2020, 244:125524.

    Google Scholar Pub Med

    [188] CARIGNAN C C, ABDALLAH M A, WU N, et al. Predictors of tetrabromobisphenol-A (TBBP-A) and hexabromocyclododecanes (HBCD) in milk from Boston mothers[J]. Environmental Science & Technology, 2012, 46(21):12146-12153.

    Google Scholar Pub Med

    [189] ROOSENS L, D HOLLANDER W, BERVOETS L, et al. Brominated flame retardants and perfluorinated chemicals, two groups of persistent contaminants in Belgian human blood and milk[J]. Environmental Pollution, 2010, 158(8):2546-2552.

    Google Scholar Pub Med

    [190] BARGHI M, SHIN E, CHOI S, et al. HBCD and TBBPA in human scalp hair:Evidence of internal exposure[J]. Chemosphere, 2018, 207:70-77.

    Google Scholar Pub Med

    [191] MVLLER M H B, POLDER A, BRYNILDSRUD O B, et al. Prenatal exposure to persistent organic pollutants in northern Tanzania and their distribution between breast milk, maternal blood, placenta and cord blood[J]. Environmental Research, 2019, 170:433-442.

    Google Scholar Pub Med

    [192] YANAGISAWA R, KOIKE E, WIN-SHWE T, et al. Impaired lipid and glucose homeostasis in hexabromocyclododecane-exposed mice fed a high-fat diet[J]. Environmental Health Perspectives, 2014, 122(3):277-283.

    Google Scholar Pub Med

    [193] FUJⅡ Y, NISHIMURA E, KATO Y, et al. Dietary exposure to phenolic and methoxylated organohalogen contaminants in relation to their concentrations in breast milk and serum in Japan[J]. Environment International, 2014, 63:19-25.

    Google Scholar Pub Med

    [194] KIM U, OH J. Tetrabromobisphenol A and hexabromocyclododecane flame retardants in infant-mother paired serum samples, and their relationships with thyroid hormones and environmental factors[J]. Environmental Pollution, 2014, 184:193-200.

    Google Scholar Pub Med

    [195] LIANG J, LIU S, LIU T, et al. Association of prenatal exposure to bisphenols and birth size in Zhuang ethnic newborns[J]. Chemosphere, 2020, 252:126422.

    Google Scholar Pub Med

    [196] OUIDIR M, BUCK LOUIS G M, KANNER J, et al. Association of maternal exposure to persistent organic pollutants in early pregnancy with fetal growth[J]. JAMA Pediatrics, 2020, 174(2):149-161.

    Google Scholar Pub Med

    [197] LIANG S, XU F, TANG W, et al. Brominated flame retardants in the hair and serum samples from an e-waste recycling area in southeastern China:The possibility of using hair for biomonitoring[J]. Environmental Science & Pollution Research, 2016, 23(15):14889-14897.

    Google Scholar Pub Med

    [198] SHI Z, ZHANG L, ZHAO Y, et al. A national survey of tetrabromobisphenol-A, hexabromocyclododecane and decabrominated diphenyl ether in human milk from China:Occurrence and exposure assessment[J]. Science of the Total Environment, 2017, 599/600:237-245.

    Google Scholar Pub Med

    [199] LI A, ZHUANG T, SHI W, et al. Serum concentration of bisphenol analogues in pregnant women in China[J]. Science of the Total Environment, 2020, 707:136100.

    Google Scholar Pub Med

    [200] RAWN D F K, RYAN J J, SADLER A R, et al. Brominated flame retardant concentrations in sera from the Canadian health measures survey (CHMS) from 2007 to 2009[J]. Environment International, 2014, 63:26-34.

    Google Scholar Pub Med

    [201] BJERMO H, AUNE M, CANTILLANA T, et al. Serum levels of brominated flame retardants (BFRs:PBDE, HBCD) and influence of dietary factors in a population-based study on Swedish adults[J]. Chemosphere, 2017, 167:485-491.

    Google Scholar Pub Med

    [202] LANKOVA D, LACINA O, PULKRABOVA J, et al. The determination of perfluoroalkyl substances, brominated flame retardants and their metabolites in human breast milk and infant formula[J]. Talanta, 2013, 117:318-325.

    Google Scholar Pub Med

    [203] PRATT I, ANDERSON W, CROWLEY D, et al. Brominated and fluorinated organic pollutants in the breast milk of first-time Irish mothers:is there a relationship to levels in food?[J]. Food Additives & Contaminants:Part A, 2013, 30(10):1788-1798.

    Google Scholar Pub Med

    [204] WEMKEN N, DRAGE D S, CELLARIUS C, et al. Emerging and legacy brominated flame retardants in the breast milk of first time Irish mothers suggest positive response to restrictions on use of HBCDD and penta-and octa-BDE formulations[J]. Environmental Research, 2020, 180:108805.

    Google Scholar Pub Med

    [205] INTHAVONG C, HOMMET F, BORDET F, et al. Simultaneous liquid chromatography-tandem mass spectrometry analysis of brominated flame retardants (tetrabromobisphenol A and hexabromocyclododecane diastereoisomers) in French breast milk[J]. Chemosphere, 2017, 186:762-769.

    Google Scholar Pub Med

    [206] THOMSEN C, KNUTSEN H K, LIANE V H, et al. Consumption of fish from a contaminated lake strongly affects the concentrations of polybrominated diphenyl ethers and hexabromocyclododecane in serum[J]. Molecular Nutrition & Food Research, 2008, 52(2):228-237.

    Google Scholar Pub Med

    [207] DUFOUR P, PIRARD C, CHARLIER C. Determination of phenolic organohalogens in human serum from a Belgian population and assessment of parameters affecting the human contamination[J]. Science of the Total Environment, 2017, 599/600:1856-1866.

    Google Scholar Pub Med

    [208] ABDALLAH M A, HARRAD S. Polybrominated diphenyl ethers in UK human milk:Implications for infant exposure and relationship to external exposure[J]. Environment International, 2014, 63:130-136.

    Google Scholar Pub Med

    [209] TADEO J L, SÁNCHEZ-BRUNETE C, MIGUEL E. Determination of polybrominated diphenyl ethers in human hair by gas chromatography-mass spectrometry[J]. Talanta, 2009, 78(1):138-143.

    Google Scholar Pub Med

    [210] KRÓL S, NAMIEŚNIK J, ZABIEGAŁA B. Occurrence and levels of polybrominated diphenyl ethers (PBDEs) in house dust and hair samples from northern Poland; An assessment of human exposure[J]. Chemosphere, 2014, 110:91-96.

    Google Scholar Pub Med

    [211] MAMORU M, TOMOHIKO I, KARRI R, et al. Contamination of brominated flame retardants (BFRs) in human hair from e-waste recycling site in Vietnam. Interdiscip[J]. Environmental Pollution & Ecotoxicology, 2012:229-237.

    Google Scholar Pub Med

    [212] POON S, WADE M, ALEKSA K, et al. Hair as a biomarker of systemic exposure to polybrominated diphenyl ethers[J]. Environmental Science & Technology, 2014, 48(24):14650-1468.

    Google Scholar Pub Med

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Research progress on status of environmental pollutions of polybrominated diphenyl ethers, hexabromocyclodocane, and tetrabromobisphenol A: A review

Fund Project: Supported by Science and Technology Project of Guangdong Province (2013B020600006), Special Fund for Introducing Talents in Colleges and Universities of Guangdong Province(Guangdong Finance Education C1067501) and Special Fund for Shenzhen Strategic Emerging Industries Development(JSGG20170823153043998).

Abstract: Polybrominated diphenyl ethers (PBDEs), hexabromocyclododecane (HBCD), and tetrabromobisphenol A (TBBPA) are the main traditional brominated flame retardants (BFRs). Owing to the property of Semi-volatility, persistance, and mobility, they are all found in various environmental media and organisms all over the world. Toxicological studies have shown that PBDEs, HBCD, and TBBPA not only exhibited obvious biological toxicity and carcinogenicity, but also posed potential harm to the ecological environment and human. This paper briefly summarized the current status of PBDEs, HBCD, and TBBPA in the environment, and discussed the level, distribution, exposure routes and toxicity of three traditional BFRs in non-living organisms (dust, water, soil, sediment, sludge) and living organisms (plants, animals, and humans). In addition, the problems existing in nowadays research were mentioned. Finally, a preliminary outlook for future research on PBDEs, HBCD, and TBBPA was presented.

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