典型抗生素二元混合物对明亮发光杆菌的急性联合毒性

丛永平, 姜蕾, 王婷, 邹小明, 葛鸿铭, 尹大强, 林志芬. 典型抗生素二元混合物对明亮发光杆菌的急性联合毒性[J]. 环境化学, 2013, 32(7): 1348-1352. doi: 10.7524/j.issn.0254-6108.2013.07.031
引用本文: 丛永平, 姜蕾, 王婷, 邹小明, 葛鸿铭, 尹大强, 林志芬. 典型抗生素二元混合物对明亮发光杆菌的急性联合毒性[J]. 环境化学, 2013, 32(7): 1348-1352. doi: 10.7524/j.issn.0254-6108.2013.07.031
CONG Yongping, JIANG Lei, WANG Ting, ZOU Xiaoming, GE Hongming, YIN Daqiang, LIN Zhifen. Acute joint toxicity of binary antibiotic mixtures on Photobacterium phosphoreum[J]. Environmental Chemistry, 2013, 32(7): 1348-1352. doi: 10.7524/j.issn.0254-6108.2013.07.031
Citation: CONG Yongping, JIANG Lei, WANG Ting, ZOU Xiaoming, GE Hongming, YIN Daqiang, LIN Zhifen. Acute joint toxicity of binary antibiotic mixtures on Photobacterium phosphoreum[J]. Environmental Chemistry, 2013, 32(7): 1348-1352. doi: 10.7524/j.issn.0254-6108.2013.07.031

典型抗生素二元混合物对明亮发光杆菌的急性联合毒性

  • 基金项目:

    同济大学污染控制与资源化研究国家重点实验室自主研究项目(PCRRY11003),国家自然科学面上基金(201177092)和中央高校基本科研业务费专项资金(0400219181)资助.

Acute joint toxicity of binary antibiotic mixtures on Photobacterium phosphoreum

  • Fund Project:
  • 摘要: 以明亮发光杆菌作为受试生物,测定了不同类型抗生素的二元混合物对明亮发光杆菌的等比急性联合毒性. 结果表明,4 类抗生素对明亮发光杆菌二元等比急性联合毒性主要呈加和效应及拮抗效应. 本研究可为水体中抗生素的联合生态风险评价和修复提供理论依据.
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    [2] Christian T, Schneider R J, Färber H A,et al. Determination of antibiotic residues in manure, soil, and surface waters[J]. Acta Hydroch Hydrob, 2003, 31(1): 36-44
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    [6] Zou S, Xu W, Zhang R,et al. Occurrence and distribution of antibiotics in coastal water of the Bohai Bay, China: Impacts of river discharge and aquaculture activities[J]. Environ Pollut, 2011, 159(10): 2913-2920
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    [8] 姜蕾, 陈书怡, 杨蓉,等. 长江三角洲地区典型废水中抗生素的初步分析[J]. 环境化学, 2008, 27(3): 371-374
    [9] Reinthaler F, Posch J, Feierl G,et al. Antibiotic resistance of E.coli in sewage and sludge[J]. Water Res, 2003, 37(8): 1685-1690
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    [12] Zou X, Zhou X, Lin Z,et al.A docking-based receptor library of antibiotics and its novel application in predicting chronic mixture toxicity for environmental risk assessment[J]. Environmental Monitoring and Assessment, 2013,185: 4513-4527
    [13] Zou X, Lin Z, Deng Z,et al.Novel approach to predicting hormetic effects of antibiotic mixtures on Vibrio fischeri[J]. Chemosphere, 2013,90(7): 2070-2076
    [14] Zou X, Lin Z, Deng Z,et al.The joint effects of sulfonamides and their potentiator on Photobacterium phosphoreum: Differences between the acute and chronic mixture toxicity mechanisms[J]. Chemosphere, 2012, 86(1): 30-35
    [15] De Zwart D, Slooff W. The Microtox as an alternative assay in the acute toxicity assessment of water pollutants[J]. Aquat Toxicol, 1983, 4(2): 129-138
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  • 收稿日期:  2013-02-24
丛永平, 姜蕾, 王婷, 邹小明, 葛鸿铭, 尹大强, 林志芬. 典型抗生素二元混合物对明亮发光杆菌的急性联合毒性[J]. 环境化学, 2013, 32(7): 1348-1352. doi: 10.7524/j.issn.0254-6108.2013.07.031
引用本文: 丛永平, 姜蕾, 王婷, 邹小明, 葛鸿铭, 尹大强, 林志芬. 典型抗生素二元混合物对明亮发光杆菌的急性联合毒性[J]. 环境化学, 2013, 32(7): 1348-1352. doi: 10.7524/j.issn.0254-6108.2013.07.031
CONG Yongping, JIANG Lei, WANG Ting, ZOU Xiaoming, GE Hongming, YIN Daqiang, LIN Zhifen. Acute joint toxicity of binary antibiotic mixtures on Photobacterium phosphoreum[J]. Environmental Chemistry, 2013, 32(7): 1348-1352. doi: 10.7524/j.issn.0254-6108.2013.07.031
Citation: CONG Yongping, JIANG Lei, WANG Ting, ZOU Xiaoming, GE Hongming, YIN Daqiang, LIN Zhifen. Acute joint toxicity of binary antibiotic mixtures on Photobacterium phosphoreum[J]. Environmental Chemistry, 2013, 32(7): 1348-1352. doi: 10.7524/j.issn.0254-6108.2013.07.031

典型抗生素二元混合物对明亮发光杆菌的急性联合毒性

  • 1.  同济大学环境科学与工程学院, 上海, 200092;
  • 2.  城市水资源开发利用(南方)国家工程研究中心, 上海, 200082
基金项目:

同济大学污染控制与资源化研究国家重点实验室自主研究项目(PCRRY11003),国家自然科学面上基金(201177092)和中央高校基本科研业务费专项资金(0400219181)资助.

摘要: 以明亮发光杆菌作为受试生物,测定了不同类型抗生素的二元混合物对明亮发光杆菌的等比急性联合毒性. 结果表明,4 类抗生素对明亮发光杆菌二元等比急性联合毒性主要呈加和效应及拮抗效应. 本研究可为水体中抗生素的联合生态风险评价和修复提供理论依据.

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