南四湖和东平湖表层水体中抗生素污染特征和风险评价
Contamination characteristics and risk assessment of antibiotics in surface water of Nansi Lake and Dongping Lake
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摘要: 利用固相萃取-高效液相色谱/串联质谱法测定了南四湖和东平湖表层水体中5种磺胺类、4种喹诺酮类、3种青霉素类、4种四环素类、3种大环内酯类和1种硝基咪唑类共20种抗生素的浓度水平.结果显示，南四湖和东平湖表层水体中分别检出17种和15种抗生素，检出率大于50%的抗生素分别为9种和7种，20种抗生素总浓度范围分别为75.6—209 ng·L-1和23.2—114 ng·L-1，检出浓度最高的抗生素分别为四环素和诺氟沙星，南四湖整体浓度水平高于东平湖.与其它主要河流湖泊相比，南四湖和东平湖中抗生素浓度处于中等偏下水平.环境风险评价结果表明，环丙沙星和阿莫西林的风险熵值RQ高于1.00，表现为高风险，其余抗生素为无风险、低风险或中等风险.健康风险评价表明，目前抗生素残留不会对人体产生明显的健康危害.
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关键词:
- 高效液相色谱/串联质谱 /
- 南四湖 /
- 东平湖 /
- 抗生素 /
- 风险评价
Abstract: 20 antibiotics including 5 sulfonamides, 4 quinolones, 3 penicillins, 4 tetracyclines, 3 macrolides and 1 nitromidazole in Nansi Lake and Dongping Lake were monitored with the method of solid phase extraction and high performance liquid chromatography tandem mass spectrometry. Results showed that 17 and 15 antibiotics were detectived, and the detection rates of 9 and 7 kinds of antibiotics were over 50% respectively in Nansi Lake and Dongping Lake. The total concentrations of 20 antibiotics ranged from 75.6—209 ng·L-1 and 23.2—114 ng·L-1, and the highest concentration antibiotics were tetracycline and norfloxaci respectively. The concentration level of Nansi Lake was higher than Dongping Lake. Compared with other major rivers and lakes, the concentrations of antibiotics in Nansi Lake and Dongping Lake were below the medium level. The results of environmental risk assessment indicated that the RQ of ciprofloxacin and amoxicillin were higher than 1.00, indicating high risk, and other antibiotics were no risk, low risk or medium risk. The results of health risk assessment indicated that current antibiotic residues would not cause obvious health hazard to human beings currently. -
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