微纳米塑料对鱼类的毒性效应及作用机制研究进展
Research Advances on Toxic Effects and Mechanisms of Micro- and Nano-plastics on Fish
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摘要: 微纳米塑料(MNPs)在水环境中的污染问题已成为全球关注的热点。MNPs因其数量多、粒径小,极易被鱼类误食对鱼体造成危害。本文综述了MNPs对鱼类毒性效应及作用机制,首先阐述了鱼类对MNPs的摄食、富集和转运规律,分析了不同粒径的MNPs对鱼类造成的不同危害,其次重点评述了MNPs对鱼类毒性效应及作用机制,并介绍了MNPs和其他污染物对鱼类的毒性效应,最后展望了MNPs对鱼类的研究趋势。研究MNPs对鱼类毒性效应及作用机制有利于增进对MNPs的生态毒性的认识,为经济鱼类的安全生产和生态稳定提供科学依据。Abstract: The pollution of micro- and nano-plastics (MNPs) in water environments has become a global concern. Because of their large quantity and small particle size, MNPs are prone to be ingested by fish and cause harm. This article reviews the toxic effects and the mechanisms of MNPs on fish. Firstly, the patterns of MNPs ingestion, enrichment, and transport in fish are summarized, and the stress caused by MNPs with different particle sizes are analyzed. Secondly, the toxic effects of MNPs on fish and the mechanisms are emphatically demonstrated, and the combined toxic effects of MNPs and other pollutants on fish are delineated. Finally, three research prospects of MNPs on fish are proposed. This review article is conducive to enhancing the understanding of the ecotoxicity of MNPs, providing scientific basis for the safe production and ecological stability of commercial fish.
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Key words:
- micro- and nano-plastics /
- fish /
- toxic effect /
- mechanisms
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Wang C H, Zhao J, Xing B S. Environmental source, fate, and toxicity of microplastics[J]. Journal of Hazardous Materials, 2021, 407: 124357 Kazour M, Jemaa S, El Rakwe M, et al. Juvenile fish caging as a tool for assessing microplastics contamination in estuarine fish nursery grounds[J]. Environmental Science and Pollution Research International, 2020, 27(4): 3548-3559 Amobonye A, Bhagwat P, Raveendran S, et al. Environmental impacts of microplastics and nanoplastics: A current overview[J]. Frontiers in Microbiology, 2021, 12: 768297 Jeyavani J, Sibiya A, Shanthini S, et al. A review on aquatic impacts of microplastics and its bioremediation aspects[J]. Current Pollution Reports, 2021, 7(3): 286-299 Botterell Z L R, Beaumont N, Dorrington T, et al. Bioavailability and effects of microplastics on marine zooplankton: A review[J]. Environmental Pollution, 2019, 245: 98-110 Ma C Z, Chen Q Q, Li J W, et al. Distribution and translocation of micro- and nanoplastics in fish[J]. Critical Reviews in Toxicology, 2021, 51(9): 740-753 Lim C, Kim N, Lee J, et al. Potential of adsorption of diverse environmental contaminants onto microplastics[J]. Water, 2022, 14(24): 4086 Adamovsky O, Bisesi J H, Martyniuk C J. Plastics in our water: Fish microbiomes at risk?[J]. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2021, 39: 100834 Bhuyan M S. Effects of microplastics on fish and in human health[J]. Frontiers in Environmental Science, 2022, 10: 827289 Contino M, Ferruggia G, Pecoraro R, et al. Uptake routes and biodistribution of polystyrene nanoplastics on zebrafish larvae and toxic effects on development[J]. Fishes, 2023, 8(3): 168 Pradit S, Noppradit P, Jitkaew P, et al. Microplastic accumulation in catfish and its effects on fish eggs from Songkhla Lagoon, Thailand[J]. Journal of Marine Science and Engineering, 2023, 11(4): 723 Wang J, Li Y J, Lu L, et al. Polystyrene microplastics cause tissue damages, sex-specific reproductive disruption and transgenerational effects in marine medaka (Oryzias melastigma)[J]. Environmental Pollution, 2019, 254(Pt B): 113024 Jovanović B, Gökdaǧ K, Güven O, et al. Virgin microplastics are not causing imminent harm to fish after dietary exposure[J]. Marine Pollution Bulletin, 2018, 130: 123-131 Barboza L G A, Lopes C, Oliveira P, et al. Microplastics in wild fish from North East Atlantic Ocean and its potential for causing neurotoxic effects, lipid oxidative damage, and human health risks associated with ingestion exposure[J]. The Science of the Total Environment, 2020, 717: 134625 Su L, Deng H, Li B W, et al. The occurrence of microplastic in specific organs in commercially caught fishes from coast and estuary area of East China[J]. Journal of Hazardous Materials, 2019, 365: 716-724 Rakib M R J, Sarker A, Ram K, et al. Microplastic toxicity in aquatic organisms and aquatic ecosystems: A review[J]. Water, Air, & Soil Pollution, 2023, 234(1): 52 Ma Y F, You X Y. Modelling the accumulation of microplastics through food webs with the example Baiyangdian Lake, China[J]. Science of the Total Environment, 2021, 762: 144110 Zhang F, Wang X H, Xu J Y, et al. Food-web transfer of microplastics between wild caught fish and crustaceans in East China Sea[J]. Marine Pollution Bulletin, 2019, 146: 173-182 McIlwraith H K, Kim J, Helm P, et al. Evidence of microplastic translocation in wild-caught fish and implications for microplastic accumulation dynamics in food webs[J]. Environmental Science & Technology, 2021, 55(18): 12372-12382 Fytianos G, Ioannidou E, Thysiadou A, et al. Microplastics in Mediterranean coastal countries: A recent overview[J]. Journal of Marine Science and Engineering, 2021, 9(1): 98 Miloloža M, Kučić Grgić D, Bolanča T, et al. Ecotoxicological assessment of microplastics in freshwater sources: A review[J]. Water, 2020, 13(1): 56 赵佳, 饶本强, 郭秀梅, 等. 微塑料对斑马鱼胚胎孵化影响及其在幼鱼肠道中的积累[J]. 环境科学, 2021, 42(1): 485-491 Zhao J, Rao B Q, Guo X M, et al. Effects of microplastics on embryo hatching and intestinal accumulation in larval zebrafish Danio rerio[J]. Environmental Science, 2021, 42(1): 485-491(in Chinese)
Yang H, Xiong H R, Mi K H, et al. Toxicity comparison of nano-sized and micron-sized microplastics to goldfish Carassius auratus larvae[J]. Journal of Hazardous Materials, 2020, 388: 122058 Kashiwada S. Distribution of nanoparticles in the see-through medaka (Oryzias latipes)[J]. Environmental Health Perspectives, 2006, 114(11): 1697-1702 Wang X Q, Jian S Q, Zhang S S, et al. Enrichment of polystyrene microplastics induces histological damage, oxidative stress, Keap1-Nrf2 signaling pathway-related gene expression in loach juveniles (Paramisgurnus dabryanus)[J]. Ecotoxicology and Environmental Safety, 2022, 237: 113540 Lu Y F, Zhang Y, Deng Y F, et al. Uptake and accumulation of polystyrene microplastics in zebrafish (Danio rerio) and toxic effects in liver[J]. Environmental Science & Technology, 2016, 50(7): 4054-4060 Limonta G, Mancia A, Abelli L, et al. Effects of microplastics on head kidney gene expression and enzymatic biomarkers in adult zebrafish[J]. Comparative Biochemistry and Physiology Toxicology & Pharmacology, 2021, 245: 109037 Usman S, Abdull Razis A F, Shaari K, et al. Polystyrene microplastics exposure: An insight into multiple organ histological alterations, oxidative stress and neurotoxicity in Javanese medaka fish (Oryzias javanicus Bleeker, 1854)[J]. International Journal of Environmental Research and Public Health, 2021, 18(18): 9449 Kaloyianni M, Bobori D C, Xanthopoulou D, et al. Toxicity and functional tissue responses of two freshwater fish after exposure to polystyrene microplastics[J]. Toxics, 2021, 9(11): 289 Wang C L, Hou M M, Shang K Y, et al. Microplastics (polystyrene) exposure induces metabolic changes in the liver of rare minnow (Gobiocypris rarus)[J]. Molecules, 2022, 27(3): 584 Brandts I, Cánovas M, Tvarijonaviciute A, et al. Nanoplastics are bioaccumulated in fish liver and muscle and cause DNA damage after a chronic exposure[J]. Environmental Research, 2022, 212(Pt A): 113433 Chisada S, Yoshida M, Karita K. Polyethylene microbeads are more critically toxic to the eyes and reproduction than the kidneys or growth in medaka, Oryzias latipes[J]. Environmental Pollution, 2021, 268: 115957 Tongo I, Erhunmwunse N O. Effects of ingestion of polyethylene microplastics on survival rate, opercular respiration rate and swimming performance of African catfish (Clarias gariepinus)[J]. Journal of Hazardous Materials, 2022, 423: 127237 Liu Y Q, Qiu X C, Xu X N, et al. Uptake and depuration kinetics of microplastics with different polymer types and particle sizes in Japanese medaka (Oryzias latipes)[J]. Ecotoxicology and Environmental Safety, 2021, 212: 112007 Alberghini L, Truant A, Santonicola S, et al. Microplastics in fish and fishery products and risks for human health: A review[J]. International Journal of Environmental Research and Public Health, 2022, 20(1): 789 Xue Y H, Feng L S, Xu Z Y, et al. The time-dependent variations of zebrafish intestine and gill after polyethylene microplastics exposure[J]. Ecotoxicology, 2021, 30(10): 1997-2010 Cao J W, Xu R, Wang F H, et al. Polyethylene microplastics trigger cell apoptosis and inflammation via inducing oxidative stress and activation of the NLRP3 inflammasome in carp gills[J]. Fish & Shellfish Immunology, 2023, 132: 108470 Xue Y H, Jia T, Yang N, et al. Transcriptome alterations in zebrafish gill after exposure to different sizes of microplastics[J]. Journal of Environmental Science and Health Part A, Toxic/Hazardous Substances & Environmental Engineering, 2022, 57(5): 347-356 Kim J H, Yu Y B, Choi J H. Toxic effects on bioaccumulation, hematological parameters, oxidative stress, immune responses and neurotoxicity in fish exposed to microplastics: A review[J]. Journal of Hazardous Materials, 2021, 413: 125423 Limonta G, Mancia A, Benkhalqui A, et al. Microplastics induce transcriptional changes, immune response and behavioral alterations in adult zebrafish[J]. Scientific Reports, 2019, 9(1): 15775 Mokhtar D M, Zaccone G, Alesci A, et al. Main components of fish immunity: An overview of the fish immune system[J]. Fishes, 2023, 8(2): 93 Kordon A O, Karsi A, Pinchuk L. Innate immune responses in fish: Antigen presenting cells and professional phagocytes[J]. Turkish Journal of Fisheries and Aquatic Sciences, 2018, 18(9): 1123-1139 Sayyaf Dezfuli B, Giari L, Bosi G. Survival of metazoan parasites in fish: Putting into context the protective immune responses of teleost fish[J]. Advances in Parasitology, 2021, 112: 77-132 Liu X Y, Liang C N, Zhou M, et al. Exposure of Cyprinus carpio var. larvae to PVC microplastics reveals significant immunological alterations and irreversible histological organ damage[J]. Ecotoxicology and Environmental Safety, 2023, 249: 114377 Zhu C X, Zhou W Z, Han M M, et al. Dietary polystyrene nanoplastics exposure alters hepatic glycolipid metabolism, triggering inflammatory responses and apoptosis in Monopterus albus[J]. The Science of the Total Environment, 2023, 891: 164460 Wang F H, Zhang Q R, Cui J, et al. Polystyrene microplastics induce endoplasmic reticulum stress, apoptosis and inflammation by disrupting the gut microbiota in carp intestines[J]. Environmental Pollution, 2023, 323: 121233 Del Piano F, Lama A, Piccolo G, et al. Impact of polystyrene microplastic exposure on gilthead seabream (Sparus aurata Linnaeus, 1758): Differential inflammatory and immune response between anterior and posterior intestine[J]. The Science of the Total Environment, 2023, 879: 163201 Xia X H, Sun M H, Zhou M, et al. Polyvinyl chloride microplastics induce growth inhibition and oxidative stress in Cyprinus carpio var. larvae[J]. The Science of the Total Environment, 2020, 716: 136479 Rangasamy B, Malafaia G, Maheswaran R. Evaluation of antioxidant response and Na+-K+-ATPase activity in zebrafish exposed to polyethylene microplastics: Shedding light on a physiological adaptation[J]. Journal of Hazardous Materials, 2022, 426: 127789 Cui J, Zhang Y H, Liu L, et al. Polystyrene microplastics induced inflammation with activating the TLR2 signal by excessive accumulation of ROS in hepatopancreas of carp (Cyprinus carpio)[J]. Ecotoxicology and Environmental Safety, 2023, 251: 114539 Yu Y B, Choi J H, Choi C Y, et al. Toxic effects of microplastic (polyethylene) exposure: Bioaccumulation, hematological parameters and antioxidant responses in crucian carp, Carassius carassius[J]. Chemosphere, 2023, 332: 138801 Li L A, Gu H X, Chang X Q, et al. Oxidative stress induced by nanoplastics in the liver of juvenile large yellow croaker Larimichthys crocea[J]. Marine Pollution Bulletin, 2021, 170: 112661 Kim J A, Kim M J, Song J A, et al. Effects of microfiber exposure on medaka (Oryzias latipes): Oxidative stress, cell damage, and mortality[J]. Comparative Biochemistry and Physiology Toxicology & Pharmacology, 2023, 265: 109535 Iheanacho S C, Odo G E. Neurotoxicity, oxidative stress biomarkers and haematological responses in African catfish (Clarias gariepinus) exposed to polyvinyl chloride microparticles[J]. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2020, 232: 108741 Huang J N, Wen B, Xu L, et al. Micro/nano-plastics cause neurobehavioral toxicity in discus fish (Symphysodon aequifasciatus): Insight from brain-gut-microbiota axis[J]. Journal of Hazardous Materials, 2022, 421: 126830 König Kardgar A, Ghosh D, Sturve J, et al. Chronic poly(l-lactide) (PLA)- microplastic ingestion affects social behavior of juvenile European perch (Perca fluviatilis)[J]. The Science of the Total Environment, 2023, 881: 163425 Chen Q Q, Lackmann C, Wang W Y, et al. Microplastics lead to hyperactive swimming behaviour in adult zebrafish[J]. Aquatic Toxicology, 2020, 224: 105521 Mak C W, Ching-Fong Yeung K, Chan K M. Acute toxic effects of polyethylene microplastic on adult zebrafish[J]. Ecotoxicology and Environmental Safety, 2019, 182: 109442 Qiang L Y, Lo L S H, Gao Y, et al. Parental exposure to polystyrene microplastics at environmentally relevant concentrations has negligible transgenerational effects on zebrafish (Danio rerio)[J]. Ecotoxicology and Environmental Safety, 2020, 206: 111382 Jiang Q C, Chen X H, Jiang H C, et al. Effects of acute exposure to polystyrene nanoplastics on the channel catfish larvae: Insights from energy metabolism and transcriptomic analysis[J]. Frontiers in Physiology, 2022, 13: 923278 Fernández-Míguez M, Puvanendran V, Burgerhout E, et al. Effects of weathered polyethylene microplastic ingestion on sexual maturation, fecundity and egg quality in maturing broodstock Atlantic cod Gadus morhua[J]. Environmental Pollution, 2023, 320: 121053 Wang S F, Li Y, Liu Q, et al. Photo-/ electro-/ piezo-catalytic elimination of environmental pollutants[J]. Journal of Photochemistry and Photobiology A: Chemistry, 2023, 437: 114435 Wang J L, Guo X, Xue J M. Biofilm-developed microplastics as vectors of pollutants in aquatic environments[J]. Environmental Science & Technology, 2021, 55(19): 12780-12790 Kinigopoulou V, Pashalidis I, Kalderis D, et al. Microplastics as carriers of inorganic and organic contaminants in the environment: A review of recent progress[J]. Journal of Molecular Liquids, 2022, 350: 118580 Fu J X, Li Y N, Peng L, et al. Distinct chemical adsorption behaviors of sulfanilamide as a model antibiotic onto weathered microplastics in complex systems[J]. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 648: 129337 Zhang F, Li D P, Yang Y W, et al. Combined effects of polystyrene microplastics and copper on antioxidant capacity, immune response and intestinal microbiota of Nile tilapia (Oreochromis niloticus)[J]. The Science of the Total Environment, 2022, 808: 152099 Wang S D, Xie S L, Wang Z L, et al. Single and combined effects of microplastics and cadmium on the cadmium accumulation and biochemical and immunity of Channa argus[J]. Biological Trace Element Research, 2022, 200(7): 3377-3387 Santos D, Perez M, Perez E, et al. Toxicity of microplastics and copper, alone or combined, in blackspot seabream (Pagellus bogaraveo) larvae[J]. Environmental Toxicology and Pharmacology, 2022, 91: 103835 Xu K H, Zhang Y D, Huang Y M, et al. Toxicological effects of microplastics and phenanthrene to zebrafish (Danio rerio)[J]. The Science of the Total Environment, 2021, 757: 143730 de Oliveira L A, Breton M C, Bastolla F M, et al. Reference genes for the normalization of gene expression in eucalyptus species[J]. Plant & Cell Physiology, 2012, 53(2): 405-422 Chandhini S, Rejish Kumar V J. Transcriptomics in aquaculture: Current status and applications[J]. Reviews in Aquaculture, 2019, 11(4): 1379-1397 Liu Y, Shang D W, Yang Y J, et al. Transcriptomic analysis provides insights into microplastic and heavy metal challenges in the line seahorse (Hippocampus erectus)[J]. Fishes, 2022, 7(6): 338 Santos D, Luzio A, Bellas J, et al. Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish[J]. Chemico-Biological Interactions, 2022, 363: 110021 Santos D, Félix L, Luzio A, et al. Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages[J]. Chemosphere, 2021, 277: 130262 Santos D, Luzio A, Matos C, et al. Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure[J]. Aquatic Toxicology, 2021, 235: 105814 Yan W, Hamid N, Deng S, et al. Individual and combined toxicogenetic effects of microplastics and heavy metals (Cd, Pb, and Zn) perturb gut microbiota homeostasis and gonadal development in marine medaka (Oryzias melastigma)[J]. Journal of Hazardous Materials, 2020, 397: 122795 Tang Y, Rong J H, Guan X F, et al. Immunotoxicity of microplastics and two persistent organic pollutants alone or in combination to a bivalve species[J]. Environmental Pollution, 2020, 258: 113845 Le Bihanic F, Clérandeau C, Cormier B, et al. Organic contaminants sorbed to microplastics affect marine medaka fish early life stages development[J]. Marine Pollution Bulletin, 2020, 154: 111059 Wang J, Li X, Li P, et al. Porous microplastics enhance polychlorinated biphenyls-induced thyroid disruption in juvenile Japanese flounder (Paralichthys olivaceus)[J]. Marine Pollution Bulletin, 2022, 174: 113289 Wang Q P, Li Y Z, Chen Y R, et al. Toxic effects of polystyrene nanoplastics and polybrominated diphenyl ethers to zebrafish (Danio rerio)[J]. Fish & Shellfish Immunology, 2022, 126: 21-33 Tarasco M, Gavaia P J, Bensimon-Brito A, et al. Effects of pristine or contaminated polyethylene microplastics on zebrafish development[J]. Chemosphere, 2022, 303(Pt 3): 135198 Menéndez-Pedriza A, Jaumot J. Interaction of environmental pollutants with microplastics: A critical review of sorption factors, bioaccumulation and ecotoxicological effects[J]. Toxics, 2020, 8(2): 40 Song X C, Zhuang W, Cui H Z, et al. Interactions of microplastics with organic, inorganic and bio-pollutants and the ecotoxicological effects on terrestrial and aquatic organisms[J]. Science of the Total Environment, 2022, 838: 156068 -

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