三丁基锡对孔雀鱼的毒性效应研究

谭燕; 李远友; 杜永兵; 陈伟州; 孙泽伟

三丁基锡对孔雀鱼的毒性效应研究

汕头大学海洋生物研究所, 汕头, 515063;

广州大学生命科学学院, 广州, 510006

基金项目:

广东省自然科学基金(32046)

国家自然科学基金(30570325)

教育部留学回国人员科研启动基金(2004-527)资助项目

ACUTE AND CHRONIC TOXIC EFFECT OF TRIBUTYLTIN ON THE GUPPIES (POECILIA RETICULATES)

Marine Biology Institute, Shantou University, Shantou, 515063, China;

School of Life Science, Guangzhou University, Guangzhou, 510006, China

Fund Project:

摘要: 采用静态暴露方式研究三丁基锡氯化物(TBTCl)对孔雀鱼的毒性效应.当幼鱼暴露于1.25-7.90μg·l-1的TBTCl 后,出现明显的急性中毒症状,96h的半致死浓度(LC50)为5.82μg·l-1; 成鱼在0.14-3.56μg·l-1浓度下暴露10-30d,TBTCl能诱导雌鱼的肝体指数升高,并使肝脏和脾脏组织的显微结构发生明显的病理变化,毒害作用具有明显的剂量-效应和时间-效应关系.表明肝体指数以及肝脏、脾脏等组织的病理学变化可以作为评估三丁基锡等环境污染物的生物指标.

Abstract: The toxic effects of tributyltin chloride(TBTCl) on the guppies(Poecilia reticulates)were estimated via the static exposure experiments.When the larva were exposed to TBTCl at the dose of 1.25—7.90μg·l-1,the acute toxic effects appeared and the 50% lethal concentration(LC50) at 96h was 5.82μg·l-1.After the adult female guppies were exposed to 0.14—3.56μg·l-1 TBTCl for 10—30 days,the hepatosomatic index(HSI) was significantly increased,and the histopathologic changes in the liver and spleen were observed. The toxicity displayed obvious time-effect and dose-effect relationship.The results suggest that HSI and histopathological changes in liver and spleen may be used as the biomarkers for monitoring and evaluating the environmental pollutants such as tributyltin,and the guppy may be a good species for monitoring the pollution of freshwater environment.

Key words:

三丁基锡对孔雀鱼的毒性效应研究

1. 汕头大学海洋生物研究所, 汕头, 515063;

2. 广州大学生命科学学院, 广州, 510006

基金项目:

广东省自然科学基金(32046)

国家自然科学基金(30570325)

教育部留学回国人员科研启动基金(2004-527)资助项目

关键词:

ACUTE AND CHRONIC TOXIC EFFECT OF TRIBUTYLTIN ON THE GUPPIES (POECILIA RETICULATES)

1. Marine Biology Institute, Shantou University, Shantou, 515063, China;

2. School of Life Science, Guangzhou University, Guangzhou, 510006, China

Fund Project:

Keywords:

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