高级搜索

加速溶剂萃取/气相色谱质谱法测定鱼类样品中的多环麝香

,  , 

downloadPDF

上一篇

下一篇

胡正君, 史亚利, 蔡亚岐. 加速溶剂萃取/气相色谱质谱法测定鱼类样品中的多环麝香[J]. 环境化学, 2011, 30(1): 362-365.
引用本文: 胡正君, 史亚利, 蔡亚岐. 加速溶剂萃取/气相色谱质谱法测定鱼类样品中的多环麝香[J]. 环境化学, 2011, 30(1): 362-365.
shu
HU Zhengjun, SHI Yali, CAI Yaqi. DETERMINATION OF POLYCYCLIC MUSKS IN FISH SAMPLES BY ACCELERATED SOVENT EXTRACTION (ASE) AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY[J]. Environmental Chemistry, 2011, 30(1): 362-365.
Citation: HU Zhengjun, SHI Yali, CAI Yaqi. DETERMINATION OF POLYCYCLIC MUSKS IN FISH SAMPLES BY ACCELERATED SOVENT EXTRACTION (ASE) AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY[J]. Environmental Chemistry, 2011, 30(1): 362-365.
shu

加速溶剂萃取/气相色谱质谱法测定鱼类样品中的多环麝香

  • 1.

    中国科学院生态环境研究中心环境化学与生态毒理学国家重点实验室, 北京, 100085

  • 基金项目:

    国家自然科学基金项目(No.20837003,20921063,20890111)

    国家973项目子课题(No.2009CB421605)资助.

DETERMINATION OF POLYCYCLIC MUSKS IN FISH SAMPLES BY ACCELERATED SOVENT EXTRACTION (ASE) AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY

  • 1.

    State Key Laboratory of Environmental Chemistry and Ecotoxicity, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China

  • Fund Project:

  • 摘要: 建立了鱼类样品中5种多环麝香的分析方法.采用加速溶剂萃取(ASE)提取,经凝胶渗透色谱(GPC)以及中性氧化铝层析柱净化后,浓缩并定容洗脱液,用GC-SIM-MS进行检测.本方法对替代物标样荧蒽-d10的回收率为92.7%—112.9%.以六氯苯(13C)为内标,5种合成麝香的线性范围为1.0—1000.0 ng·g-1.麝香的检出限为0.20—0.30 ng·g-1(S/N=3).5种化合物的基质加标回收实验的平均回收率为89.6%—110.1%,RSD为3.2%—8.8%.方法准确,可用于实际样品的检测.
    Abstract: An accelerated solvent extraction (ASE) method has been developed to determine five polycyclic musk fragrances in fish samples by GC-MS. Fish samples were extracted by n-hexane, cleaned up by gel permeation chromatography (GPC) and activated neutral Al2O3 column. The final elute was concentrated with nitrogen before injection. Identification was carried out by GC-MS selective ion monitor (SIM) mode. The recovery of fluenthene-d10, surrogate standard, was from 92.7% to 112.9%. The limits of detection were from 0.20 to 0.30 ng·g-1(S/N=3). Using hexachlorobenzene (HCB) 13C6 as the internal standard, the calibration curves were linear between the concentrations from 1.0 to 1000.0 ng·g-1. The accuracy of the method was evaluated by recovery measurements on spiked samples, and good recoveries (89.6%—110.1%) with low relative standard deviations from 3.2% to 8.8% were achieved when spiked with 100 μg·L-1 standards. The method is accurate during the inspection of synthetic musks in fish samples.
  • 加载中
  • [1] Matamoros V, Bayona J M, Elimination of pharmaceuticals and personal care products in subsurface flow constructed Wetlands[J].Environ Sci Technol, 2006, 40:5811-5816
    [2] 曾祥英,陈多宏,桂红艳,等.环境中合成麝香污染物的研究进展[J]. 环境监测管理技术, 2006, 18(3): 7-10
    [3] Berset J D, Kupper T, Etter R, et al. Considerations about the enantioselective transformation of polycyclic musks in wastewater, treated wastewater and sewage sludge and analysis of their fate in a sequencing batch reactor plant[J]. Chemosphere, 2004, 57(8): 987-996
    [4] Sumner N R, Guitart C, Fuentes G, et al. Inputs and distributions of synthetic musk fragrances in an estuarine and coastal environment; a case study. [J]. Environ Pollut, 2009, 158(1): 215-222
    [5] Toivanen N, Toimela T, Thti H. Effect of polycyclic musks on the aromatase activity in JEG-3 chorion carcinoma cells[J]. Toxicol Lett, 2008, 180(Suppl 1): S118-S118
    [6] Yamauchi R, Ishibashi H, Hirano M, et al. Effects of synthetic polycyclic musks on estrogen receptor, vitellogenin, pregnane X receptor, and cytochrome P450 3A gene expression in the livers of male medaka (Oryzias latipes) [J]. Aquat Toxicol, 2008, 90(4):261-268
    [7] 梁高锋,王珺,周静,等. 气相色谱-质谱联用测定母乳中合成麝香[J]. 环境化学,2010,29(1): 113-116
    [8] Schmid P, Kohler M, Gujer E, et al. Persistent organic pollutants, brominated flame retardants and synthetic musks in fish from remote Alpine lakes in Switzerland[J]. Chemosphere, 2007, 67(9):S16-S21
    [9] Gatermann R, Biselli S, Hühnerfass H,et al. Synthetic musks in the environment. Part 2: Enantioselective transformation of the polycyclic musk fragrances HHCB, AHTN, AHDI, and ATII in freshwater fish[J]. Arch Environ Contam Toxicol, 2002, 42(4): 447-453
    [10] 桑文静, 周雪飞, 张亚雷.城市污水厂污泥中合成麝香分析方法的研究进展[J]. 中国给水排水, 2009,25(8):17-21
    [11] Wan Y, Wei Q, Hu J, et al. Levels, tissue distribution, and age-related accumulation of synthetic musk fragrances in Chinese Sturgeon (Acipenser sinensis): comparison to organochlorines[J]. Environ Sci Technol, 2007, 41(2): 424-430
  • 加载中
WeChat 点击查看大图
计量
  • 文章访问数:  807
  • HTML全文浏览数:  807
  • PDF下载数:  327
  • 施引文献:  0
出版历程
  • 收稿日期:  2010-06-29
  • 刊出日期:  2011-01-15
胡正君, 史亚利, 蔡亚岐. 加速溶剂萃取/气相色谱质谱法测定鱼类样品中的多环麝香[J]. 环境化学, 2011, 30(1): 362-365.
引用本文: 胡正君, 史亚利, 蔡亚岐. 加速溶剂萃取/气相色谱质谱法测定鱼类样品中的多环麝香[J]. 环境化学, 2011, 30(1): 362-365.
shu
HU Zhengjun, SHI Yali, CAI Yaqi. DETERMINATION OF POLYCYCLIC MUSKS IN FISH SAMPLES BY ACCELERATED SOVENT EXTRACTION (ASE) AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY[J]. Environmental Chemistry, 2011, 30(1): 362-365.
Citation: HU Zhengjun, SHI Yali, CAI Yaqi. DETERMINATION OF POLYCYCLIC MUSKS IN FISH SAMPLES BY ACCELERATED SOVENT EXTRACTION (ASE) AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY[J]. Environmental Chemistry, 2011, 30(1): 362-365.
shu

加速溶剂萃取/气相色谱质谱法测定鱼类样品中的多环麝香

  • 1. 中国科学院生态环境研究中心环境化学与生态毒理学国家重点实验室, 北京, 100085
  • 收稿日期:  2010-06-29
基金项目:

国家自然科学基金项目(No.20837003,20921063,20890111)

国家973项目子课题(No.2009CB421605)资助.

摘要: 建立了鱼类样品中5种多环麝香的分析方法.采用加速溶剂萃取(ASE)提取,经凝胶渗透色谱(GPC)以及中性氧化铝层析柱净化后,浓缩并定容洗脱液,用GC-SIM-MS进行检测.本方法对替代物标样荧蒽-d10的回收率为92.7%—112.9%.以六氯苯(13C)为内标,5种合成麝香的线性范围为1.0—1000.0 ng·g-1.麝香的检出限为0.20—0.30 ng·g-1(S/N=3).5种化合物的基质加标回收实验的平均回收率为89.6%—110.1%,RSD为3.2%—8.8%.方法准确,可用于实际样品的检测.

English Abstract

    全文HTML

参考文献 (11)

返回顶部

目录

/

返回文章
返回

Copyright © 2019 中国科学院生态环境研究中心