高级搜索

磺胺类抗生素污染现状及其环境行为的研究进展

,  ,  ,  , 

downloadPDF

上一篇

下一篇

陈姗, 许凡, 张玮, 唐文乔, 王丽卿. 磺胺类抗生素污染现状及其环境行为的研究进展[J]. 环境化学, 2019, (7): 1557-1569. doi: 10.7524/j.issn.0254-6108.2018091901
引用本文: 陈姗, 许凡, 张玮, 唐文乔, 王丽卿. 磺胺类抗生素污染现状及其环境行为的研究进展[J]. 环境化学, 2019, (7): 1557-1569. doi: 10.7524/j.issn.0254-6108.2018091901
shu
CHEN Shan, XU Fan, ZHANG Wei, TANG Wenqiao, WANG Liqing. Research progress in pollution situation and environmental behavior of Sulfonamides[J]. Environmental Chemistry, 2019, (7): 1557-1569. doi: 10.7524/j.issn.0254-6108.2018091901
Citation: CHEN Shan, XU Fan, ZHANG Wei, TANG Wenqiao, WANG Liqing. Research progress in pollution situation and environmental behavior of Sulfonamides[J]. Environmental Chemistry, 2019, (7): 1557-1569. doi: 10.7524/j.issn.0254-6108.2018091901
shu

磺胺类抗生素污染现状及其环境行为的研究进展

  • 1. 上海海洋大学农业部鱼类营养与环境生态研究中心, 上海, 201306;

  • 2. 上海海洋大学水产种质资源发掘与利用教育部重点实验室, 上海, 201306;

  • 3. 上海海洋大学水产科学国家级实验教学示范中心, 上海, 201306

    • 通讯作者: 张玮, E-mail: weizhang@shou.edu.cn ;  王丽卿, E-mail: lqwang@shou.edu.cn
  • 基金项目:

    十三五国家水体污染控制与治理科技重大专项（2017ZX07207002-03）资助.

Research progress in pollution situation and environmental behavior of Sulfonamides

  • 1. Centre for Research on Environmental Ecology and Fish Nutrient of the Ministry of Agriculture, Shanghai, 201306, China;

  • 2. Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai, 201306, China;

  • 3. National Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, 201306, China

    • Corresponding authors: ZHANG Wei, weizhang@shou.edu.cn ;  WANG Liqing, lqwang@shou.edu.cn
  • Fund Project: Supported by the Major Water Pollution Control and Treatment Science and Technology Project of National "Thirteenth Five-Year" Plan (2017ZX07207002-03).

  • 摘要: 抗生素广泛应用于医疗、畜牧业和水产养殖业，但过量使用可对环境产生危害.磺胺类抗生素是一类常用的兽用抗生素，具有成本低、抗菌谱广等特性，能预防动物疾病和促进机体生长，被广泛应用于世界各地.然而，磺胺类抗生素难被机体吸收，常随粪便和尿液排出体外，继而发生一系列的环境行为，并造成环境污染.本文介绍了抗生素的分类、来源及危害，重点阐述了磺胺类抗生素的国内外污染现状、环境行为和毒性效应，为后续治理抗生素污染提供基础资料.
    Abstract: Antibiotics are widely used in pharmaceuticals industry, animal husbandry and aquaculture. However, excessive use of antibiotics can cause harm to the environment. Sulfonamides are a group of commonly used veterinary antibiotics, which have low cost and broad-spectrum antibacterial activity. And it can prevent animal diseases and promote the growth of animals. However, sulfonamides are poorly absorbed by animal body, and often excreted unchanged in faeces and urine, subsequently suffering a series of environmental behaviors and causing environmental pollution. This review introduced the classification, source and hazard of antibiotics, and elaborated on the pollution situation, environmental behavior and toxic effect of sulfonamides at domestic and foreign, in order to provide basic information for the subsequent treatment of antibiotic pollution.
  • 加载中
  • [1] 东天,马溪平,王闻烨,等. 抗生素光降解研究进展[J]. 环境科学与技术,2014,37(S1):108-113.

    DONG T,MA X P,WANG W Y,et al. Research progress on photodegradation of antibiotics[J]. Environmental Science & Technology,2014,37(S1):108-113(in Chinese).

    [2] 彭艳,丁世敏,刘蕖,等. 水环境中抗生素的光化学降解研究进展[J]. 广州化工,2016,44(10):14-17.

    PENG Y,DING S M,LIU Q,et al. Research progress on photochemical degradation of antibiotics in water environment[J]. Guangzhou Chemical Industry,2016,44(10):14-17(in Chinese).

    [3] 王路光,朱晓磊,王靖飞,等. 环境水体中的残留抗生素及其潜在风险[J]. 工业水处理,2009,29(5):10-14.

    WANG L G,ZHU X L,WANG J F,et al. Antibiotic residual in environmental water body and its potential risks[J]. Industrial Water Treatment,2009,29(5):10-14(in Chinese).

    [4] 汪涛,杨再福,陈勇航,等. 磺胺类抗性基因的产生及演变研究进展[J]. 环境污染与防治,2017,39(11):1251-1255.

    WANG T,YANG Z F,CHEN Y H,et al. Review on the ptoduction and evolution of sulfonamide resistance genes[J]. Environmental Pollution & Control,2017,39(11):1251-1255(in Chinese).

    [5] BOXALL A B A,KOLPIN D W,HALLING-SORENSEN B,et al. Are veterinary medicines causing environment risks?[J]. Environmental Science & Technology,2003,37(15):286-294.
    [6] 唐松林. 单分散聚合物SPE微球的合成及其在抗生素等新兴有机污染物检测中的应用[D]. 南京:南京大学,2014. TANG S L. Synthesis of mono-dispersed polumeric microspheres and their application to SPE of detection of antibiotics and other emerging organic contaminants[D]. Nanjing:Nanjing University,2014(in Chinese).
    [7] 吴维. 天津市供水系统中抗生素检测与控制方法的研究[D]. 天津:天津大学,2012. WU W. Study on determination and controling antibiotics in water supply system in Tianjin[D]. Tianjin:Tianjin University,2012(in Chinese).
    [8] 孙丰霞. 污水处理系统中磺胺嘧啶和磺胺甲噁唑的优化处理研究[D]. 泰安:山东农业大学,2014. SUN F X. Study on opyimizational treatment of Sulfadiazine and Sulfamethoxazole in the sewage treatment system[D]. Taian:Shandong Agricultural University,2014(in Chinese).
    [9] SARMAH A K,MEYER M T,BOXALL A B. A global perspective on the use,sales,exposure pathways,occurrence,fate and effects of veterinary antibiotics (VAs) in the environment[J]. Chemosphere,2006,65(5):725-759.
    [10] KIM K R,OWENS G,KWON S I,et al. Occurrence and environmental fate of veterinary antibiotics in the terrestrial environment[J]. Water Air Soil Pollution,2011,214(1-4):163-174.
    [11] 张伦. 磺胺类药物产销现状及趋势[J]. 中国药房,2005,16(8):571-573.

    ZHANG L. The current situation in production,marketing and tendency of sulfonamides[J]. China Pharmacy,2005,16(8):571-573(in Chinese).

    [12] HIRSCH R,TERNES T,HABERER K,et al. Occurrence of antibiotics in the aquatic environment[J]. Science of the Total Environment,1999,225(1-2):109-118.
    [13] 杨灿. 2种磺胺类抗生素在草甸黑土中的吸附/解吸及淋溶特性研究[D]. 长春:吉林农业大学,2015. YANG C. The adsorption/desorption and leaching properties of 2 Sulfa Antibiotics in meadow black soil[D]. Changchun:Jilin Agricultural University,2015(in Chinese).
    [14] ZHANG Q Q,YING G G,PAN C G,et al. Comprehensive evaluation of antibiotics emission and fate in the river basins of China:Source analysis,multimedia modeling,and linkage to bacterial resistance[J]. Environmental Science & Technology,2015,49(11):6772-6782.
    [15] LUO Y,XU L,RYSZ M,et al. Occurrence and transport of tetracycline,sulfonamide,quinolone,and macrolide antibiotics in the Haihe River Basin,China[J]. Environmental Science & Technology,2011,45(5):1827-1833.
    [16] 徐维海,张干,邹世春,等. 香港维多利亚港和珠江广州河段水体中抗生素的含量特征及其季节变化[J]. 环境科学,2006,27(12):2458-2462.

    XU W H,ZHANG G,ZOU S C,et al. Occurrence and seasonal changes of antibiotics in the Victoria Harbour and the Pearl River,South China[J]. Environmental Science,2006,27(12):2458-2462(in Chinese).

    [17] KOLPIN D W,FURLONG E T,MEYER M T,et al. Pharmaceuticals,Hormones,and other organic wastewater contaminants in US streams,1999-2000:A national reconnaissance[J]. Environmental Science & Technology,2002,36(6):1202-1211.
    [18] WATKINSON A J,MURBY E J,KOLPIN D W,et al. The occurrence of antibiotics in an urban watershed:From wastewater to drinking water[J]. Science of the Total Environment,2009,407(8):2711-2723.
    [19] 叶计朋,邹世春,张干,等. 典型抗生素类药物在珠江三角洲水体中的污染特征[J]. 生态环境,2007,16(2):384-388.

    YE J P,ZOU S C,ZHANG G,et al. Characteristics of selected antibiotics in the aquatic environment of the Pearl River Delta,south China[J]. Ecology and Environmental Sciences,2007,16(2):384-388(in Chinese).

    [20] KIM S D,CHO J,KIM I S,et al. Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface,drinking,and waste waters[J]. Water Research,2007,41(5):1013-1021.
    [21] YAN C,YANG Y,ZHOU J,et al. Antibiotics in the surface water of the Yangtze Estuary:Occurrence,distribution and risk assessment[J]. Environmental Science,2013,175:22-29.
    [22] CUI C,HAN Q,JIANG L,et al. Occurrence,distribution,and seasonal variation of antibiotics in an artificial water source reservoir in the Yangtze River delta,East China[J]. Environmental Science and Pollution Research International,2018,25(20):19393-19402.
    [23] JIANG L,HU X,YIN D,et al. Occurrence,distribution and seasonal variation of antibiotics in the Huangpu River,Shanghai,China[J]. Chemosphere,2011,82(6):822-828.
    [24] 沈群辉,冀秀玲,傅淑珺,等. 黄浦江水域抗生素及抗性基因污染初步研究[J]. 生态环境学报,2012,21(10):1717-1723.

    SHEN Q H,JI X L,FU S J,et al. Preliminary sudies on the pollution levels of antibiotic and antibiotic resistance genes in Huangpu River,China[J]. Ecology and Environmental Sciences,2012,21(10):1717-1723(in Chinese).

    [25] CAMPAGNOLO E R,JOHNSON K R,KARPATI A,et al. Antimicrobial residues in animal waste and water resources proximal to large-scale swine and poultry feeding operations[J]. Science of the Total Environment,2002,299(1):89-95.
    [26] WEI R,GE F,HUANG S,et al. Occurrence of veterinary antibiotics in animal wastewater and surface water around farms in Jiangsu Province,China[J]. Chemosphere,2011,82(10):1408-1414.
    [27] 姜蕾,陈书怡,杨蓉,等. 长江三角洲地区典型废水中抗生素的初步分析[J]. 环境化学,2008,27(3):371-374.

    JIANG L,CHEN S Y,YANG R,et al. Occurance of antibiotics in the aquatic environment of the Changjiang Delta,China[J]. Environmental Chemistry,2008,27(3):371-374(in chinese).

    [28] TONG L,LI P,WANG Y,et al. Analysis of veterinary antibiotic residues in swine wastewater and environmental water samples using optimized SPE-LC/MS/MS[J]. Chemosphere,2009,74(8):1090-1097.
    [29] 国彬,姚丽贤,刘忠珍,等. 广州市兽用抗生素的环境残留研究[J]. 农业环境科学学报,2011,30(5):938-945.

    GUO B,YAO L X,LIU Z Z,et al. Environmental residues of veterinary antibiotics in Guangzhou City,China[J]. Journal of Agro-Environment Science,2011,30(5):938-945(in Chinese).

    [30] 王敏,俞慎,洪有为,等. 5种典型滨海养殖水体中多种类抗生素的残留特性[J]. 生态环境学报,2011,20(5):934-939.

    WANG M,YU S,HONG Y W,et al. Residual characterization of multi-categorized antibiotics in five typical aquaculture waters[J]. Ecology and Environmental Sciences,2011,20(5):934-939(in Chinese).

    [31] BEN W,PAN X,QIANG Z. Occurrence and partition of antibiotics in the liquid and solid phases of swine wastewater from concentrated animal feeding operations in Shandong Province,China[J]. Environmental Science:Processes & Impacts,2013,15(4):870-875.
    [32] 阮悦斐,陈继淼,郭昌胜,等. 天津近郊地区淡水养殖水体的表层水及沉积物中典型抗生素的残留分析[J]. 农业环境科学学报,2011,30(12):2586-2593.

    RUAN Y F,CHEN J M,GUO C S,et al. Distribution characteristics of typical antibiotics in surface water and sediments from freshwater aquaculture water in Tianjin Suburban Areas,China[J]. Journal of Agro-Environment Science,2011,30(12):2586-2593(in Chinese).

    [33] DIAZ-CRUZ M S,GARCIA-GALAN M J,BARCELO D. Highly sensitive simultaneous determination of sulfonamide antibiotics and one metabolite in environmental waters by liquid chromatography-quadrupole linear ion trap-mass spectrometry[J]. Journal of Chromatography A,2008,1193(1-2):50-59.
    [34] 常红,胡建英,王乐征,等. 城市污水处理厂中磺胺类抗生素的调查研究[J]. 科学通报,2008,53(2):159-164.

    CHANG H,HU J Y,WANG L Z,et al. Investigation of Sulfonamides in urban sewage treatment plants[J]. Chinese Science Bulletin,2008,53(2):159-164(in Chinese).

    [35] 徐维海,张干,邹世春,等. 典型抗生素类药物在城市污水处理厂中的含量水平及其行为特征[J]. 环境科学,2007,28(8):1779-1783.

    XU W H,ZHANG G,ZOU S C,et al. Occurrence,distribution and fate of antibiotics in sewage treatment plants[J]. Environmental Science,2007,28(8):1779-1783(in Chinese).

    [36] BEST E P,ZAPPI M E,FREDRICKSON H L,et al. Screening of aquatic and wetland plant species for phytoremediation of explosives-contaminated groundwater from the Iowa Army Ammunition Plant[J]. Annals of the New York Academy of Sciences,2010,829(1):179-194.
    [37] HOLM J V,RUEGGE K,BJERG PL,et al. Occurrence and distribution of pharmaceutical organic compounds in the groundwater downgradient of a landfill (Grindsted,Denmark)[J]. Environmental Science & Technology,1995,29(12):3074.
    [38] SACHER F,LANGE F T,BRAUCH H J,et al. Pharmaceuticals in groundwaters:Analytical methods and results of a monitoring program in Baden-Württemberg,Germany[J]. Journal of Chromatography A,2001,938(1):199-210.
    [39] 洪蕾洁,石璐,张亚雷,等. 固相萃取-高效液相色谱法同时测定水体中的10种磺胺类抗生素[J]. 环境科学,2012,33(2):652-657.

    HONG L J,SHI L,ZHANG Y L,et al. Simultaneous determination of 10 sulfonamide antibiotics in water by solidphase extraction and high performance liquid chromatograph[J]. Environmental Science,2012,33(2):652-657(in Chinese).

    [40] GARCIA-GALAN M J,DIAZ-CRUZ S,BARCELO D. Multiresidue trace analysis of Sulfonamide Antibiotics and their metabolites in soils and sewage sludge by pressurized liquid extraction followed by liquid chromatography-electrospray-quadrupole linear ion trap mass spectrometry[J].Journal of Chromatography A,2013,1275:32-40.
    [41] 国彬,姚丽贤,何兆桓,等. 土壤中磺胺类抗生素的检测方法优化及残留、降解研究[J]. 土壤通报,2012,43(2):386-390.

    GUO B,YAO L X,HE Z H,et al. Method optimization for determination of sulfonamides and their residual and degradation in soils[J]. Chinese Journal of Soil Science,2012,43(2):386-390(in Chinese).

    [42] 沈群辉. 养殖场及周边农田土壤抗生素抗性基因和重金属污染初步研究[D]. 上海:东华大学,2013. SHEN Q H. Preliminary studies on the pollution leverls of antibiotic resistance genes and heavy metals in feelots and agricultual solis adjacent to feedlots in Shanghai,China[D]. Shanghai:Donghua University,2013(in Chinese).
    [43] LE T X,MUNEKAGE Y,KATO S. Antibiotic resistance in bacteria from shrimp farming in mangrove areas[J]. Science of the Total Environment,2005,349(1-3):95-105.
    [44] ZHOU L J,YING G G,ZHAO J L,et al. Trends in the occurrence of human and veterinary antibiotics in the sediments of the Yellow River,Hai River and Liao River in northern China[J]. Environmental Science,2011,159(7):1877-1885.
    [45] 梁惜梅,施震,黄小平. 珠江口典型水产养殖区抗生素的污染特征[J]. 生态环境学报,2013,22(2):304-310.

    LIANG X M,SHI Z,HUANG X P. Occurrence of antibiotics in typical aquaculture of the Pearl River Estuary[J]. Ecology and Environmental Sciences,2013,22(2):304-310(in Chinese).

    [46] BOXALL A,BLACKWELL P,CAVALLO R,et al. The sorption and transport of a sulphonamide antibiotic in soil systems[J]. Toxicology Letters,2002,131(1):19-28.
    [47] KAY P,BLACKWELL P A,BOXALL A B. Fate of veterinary antibiotics in a macroporous tile drained clay soil[J]. Environmental Toxicology & Chemistry,2010,23(5):1136-1144.
    [48] KAY P,BLACKWELL P A,BOXALL A B A. A lysimeter experiment to investigate the leaching of veterinary antibiotics through a clay soil and comparison with field data[J]. Environmental Pollution,2005,134(2):333-341.
    [49] LERTPAITOONPAN W,ONG S K,MOORMAN T B. Effect of organic carbon and pH on soil sorption of sulfamethazine[J]. Chemosphere,2009,76(4):558-564.
    [50] SUKUL P,LAMSHOFT M,ZUHLKE S,et al. Sorption and desorption of sulfadiazine in soil and soil-manure systems[J]. Chemosphere,2008,73(8):1344-1350.
    [51] 陈昦,张劲强,钟明,等. 磺胺类药物在太湖地区典型水稻土上的吸附特征[J]. 中国环境科学,2008,28(4):309-312.

    CHEN H,ZHANG J Q,ZHONG M,et al. Adsorption of Sulfonamides on paddy soil of Taihu Lake regeion[J]. China Environmental Science,2008,28(4):309-312(in Chinese).

    [52] 吴娜娜,钱虹,李亚峰. 水中磺胺类抗生素去除技术研究进展[J]. 建筑与预算,2017(6):43-50. WU N N,QIAN H,LI Y F. Research progress in the removal of Sulfonamides in water[J]. Construction Budget,2017

    (6):43-50(in Chinese).

    [53] 徐浩. 海口市城区地表水中抗生素残留状况调査和典型抗生素光降解模拟实验研究[D]. 海口:海南大学,2013. XU H. The Study of simultaneous setermination of 6 antibiotics and the concentration characteristics of antibiotics in HaiKou surface water and photodegradation of antibiotics[D]. Haikou:Hainan University,2013(in Chinese).
    [54] ZEPP R G,BAUGHMAN G L,SCHLOTZHAUER P F. Comparison of photochemical behavior of various humic substances in water:I. Sunlight induced reactions of aquatic pollutants photosensitized by humic substances[J]. Chemosphere,1981,10(1):109-117.
    [55] ABELLÁN M N,BAYARRI B,GIMÉNEZ J,et al. Photocatalytic degradation of sulfamethoxazole in aqueous suspension of TiO2[J]. Applied Catalysis B:Environmental,2007,74(3-4):233-241.
    [56] 孙兴霞,许毓. 水中磺胺类抗生素的光降解及富里酸对其光降解的影响[J]. 中国科学技术大学学报,2013,43(8):654-660.

    SUN X X,XU Y. Photodegradation of Sulfa Antibiotics and the impact of fulvic acids on it in water[J]. Journal of University of Science and Technology of China,2013,43(8):654-660(in Chinese).

    [57] BATISTA A P S,PIRES F C C,TEIXEIRA A C S C. Photochemical degradation of Sulfadiazine,Sulfamerazine and Sulfamethazine:Relevance of concentration and heterocyclic aromatic groups to degradation kinetics[J]. Journal of Photochemistry and Photobiology A:Chemistry,2014,286:40-46.
    [58] HUANG C H,RENEW J E,SMEBY K L. Assessment of potential antibiotic contaminants in water and preliminary occurrence analysis[J]. Journal of Contemporary Water Research & Education,2001,120(1):30-40.
    [59] HALLINGSØRENSEN B. Algal toxicity of antibacterial agents used in intensive farming[J]. Chemosphere,2000,40(7):731-739.
    [60] TROVÓ A G,NOGUEIRA R F,AGUERA A,et al. Degradation of Sulfamethoxazole in water by solar photo-Fenton. Chemical and toxicological evaluation[J]. Water Research,2009,43(16):3922-3931.
    [61] TROVÓ A G,NOGUEIRA R F,AGUERA A,et al. Photodegradation of Sulfamethoxazole in various aqueous media:persistence,toxicity and photoproducts assessment[J]. Chemosphere,2009,77(10):1292-1298.
    [62] 刘娟. 磺胺类抗生素在城市污水处理厂的分布与迁移转化研究[D]. 邯郸:河北工程大学,2012. LIU J. The occurrence and transformation of Sulfonamide Antibiotics in municipal wastewater treatment plant[D]. Handan:Hebei University of Engineering,2012(in Chinese).
    [63] JI Y,FERRONATO C,SALVADOR A,et al. Degradation of ciprofloxacin and Sulfamethoxazole by ferrous-activated persulfate:Implications for remediation of groundwater contaminated by antibiotics[J]. Science of the Total Environment,2014,472:800-808.
    [64] 薛罡,钭晨,江晨舟. 臭氧化降解给水系统中磺胺甲噁唑的试验研究[J]. 水处理技术,2010,36(3):67-69

    ,77. XUE G,DOU C,JIANG C Z. Investgation on the degradation of Sulfamethoxazole in water supply system by ozonization[J].Technology of Water Treatment,2010,36(3):67-69,77(in Chinese).

    [65] 宋存义,汪翠萍,李晖. 污水处理中几种去除药物及个人护理用品方法的机理及效果比较[J]. 环境工程学报,2009,3(11):1921-1930.

    SONG C Y,WANG C P,LI H. Mechanism and efficiency comparison between techniques of removing pharmaceuticals and personal care products in waste water treatmen[J]. Chinese Journal of Environmental Engineering,2009,3(11):1921-1930(in Chinese).

    [66] 张从良,王岩,王福安. 磺胺类药物在土壤中的微生物降解[J]. 农业环境科学学报,2007,26(5):1658-1662.

    ZHANG C L,WANG Y,WANG F A. Microbial degradation of Sulfonamides in soils[J]. Journal of Agro-Environment Science,2007,26(5):1658-1662(in Chinese).

    [67] AL-AHMAD A,DASCHNER F D,KUMMERER K. Biodegradability of cefotiam,ciprofloxacin,meropenem,penicillin G,and sulfamethoxazole and inhibition of waste water bacteria[J]. Archives of Environmental Contamination & Toxicology,1999,37(2):158-163.
    [68] INGERSLEV F,HALLING-SØRENSEN B. Biodegradability properties of Sulfonamides in activated sludge[J]. Environmental Toxicology & Chemistry,2010,19(10):2467-2473.
    [69] GONZÁLEZ O,ESPLUGAS M,SANS C,et al. Performance of a sequencing batch biofilm reactor for the treatment of pre-oxidized Sulfamethoxazole solutions[J]. Water Research,2009,43(8):2149-2158.
    [70] GUO R,CHEN J. Application of alga-activated sludge combined system (AASCS) as a novel treatment to remove Cephalosporins[J]. Chemical Engineering Journal,2015,260:550-556.
    [71] ALEXY R,KUMPEL T,KUMMERER K. Assessment of degradation of 18 antibiotics in the closed bottle test[J]. Chemosphere,2004,57(6):505-512.
    [72] NEWMAN L A,REYNOLDS C M. Phytodegradation of organic compounds[J]. Current Opinion and Technology,2004,15(3):225-230.
    [73] SUSARLA S,MEDINA V F,MCCUTCHEON S C. Phytoremediation:An ecological solution to organic chemical contamination[J]. Ecological Engineering,2002,18(5):647-658.
    [74] LIU F,YING G G,TAO R,et al. Effects of six selected antibiotics on plant growth and soil microbial and enzymatic activities[J]. Environmental Science,2009,157(5):1636-1642.
    [75] DOLLIVER H,KUMAR K,GUPTA S. Sulfamethazine uptake by plants from manure-amended soil[J]. Journal of Environment Quality,2007,36(4):1224-1230.
    [76] MIGLIORE L,BRAMBILLA G,COZZOLINO S,et al. Effect on plants of Sulphadimethoxine used in intensive farming (Panicum miliaceum,Pisum sativum and Zea mays)[J]. Agriculture Ecosystems & Environment,1995,52(2-3):103-110.
    [77] MIGLIORE L,BRAMBILLA G,CASORIA P,et al. Effect of Sulphadimethoxine contamination on barley (Hordeum distichum L,Poaceae,Liliposida)[J]. Agriculture Ecosystems & Environment,1996,60(2):121-128.
    [78] MIGLIORE L,CIVITAREALE C,BRAMBILLA G,et al. Effects of Sulphadimethoxine on cosmopolitan weeds (Amaranthus retroflexus L,Plantago major L. and Rumex acetosella L.)[J]. Agriculture Ecosystems & Environment,1997,65(2):163-168.
    [79] 赵涛,丘锦荣,蒋成爱,等. 水环境中磺胺类抗生素的污染现状与处理技术研究进展[J]. 环境污染与防治,2017,39(10):1147-1152.

    ZHAO T,QIU J R,JIANG C A,et al. Research progress in pollution status and treatment technologies of Sulfonamides in aquatic environment[J]. Environmental Pollution & Control,2017,39(10):1147-1152(in Chinese).

    [80] HUANG D J,HOU J H,KUO T F,et al. Toxicity of the veterinary sulfonamide antibiotic sulfamonomethoxine to five aquatic organisms. Environmental Toxicology and Pharmacology,2014,38:874-880.
    [81] KIM Y,CHOI K,JUNG J,et al. Aquatic toxicity of acetaminophen,carbamazepine,cimetidine,diltiazem and six major sulfonamides,and their potential ecological risks in Korea[J]. Environment International,2007,33:370-375.
    [82] LIU B Y,NIE X P,LIU W Q,et al. Toxic effects of erythromycin,ciprofloxacin and sulfamethoxazole on photosynthetic apparatus in Selenastrum capricornutum[J]. Ecotoxicology and Environmental Safety,2011,74:1027-1035.
    [83] BARAN W,SOCHACKA J,WARDAS W. Toxicity and biodegradability of sulfonamides and products of their photocatalytic degradation in aqueous solutions[J]. Chemosphere,2006,65(8):1295-1299.
    [84] SHARMA V K,MISHRA S K,NESNAS N. Oxidation of sulfonamide antimicrobials by ferrate(VI)[FeVIO2-4] [J]. Environmental Science & Technology,2006,40(23):7222-7227.
    [85] DODD M C,HUANG C H. Transformation of the antibacterial agent Sulfamethoxazole in reactions with chlorine:Kinetics,mechanisms,and pathways[J]. Environmental Science & Technology,2004,38(21):5607-5615.
  • 加载中
WeChat 点击查看大图
计量
  • 文章访问数:  4135
  • HTML全文浏览数:  4135
  • PDF下载数:  340
  • 施引文献:  0
出版历程
  • 收稿日期:  2018-09-19

磺胺类抗生素污染现状及其环境行为的研究进展

    通讯作者: 张玮, E-mail: weizhang@shou.edu.cn ;  王丽卿, E-mail: lqwang@shou.edu.cn
  • 1. 上海海洋大学农业部鱼类营养与环境生态研究中心, 上海, 201306;
  • 2. 上海海洋大学水产种质资源发掘与利用教育部重点实验室, 上海, 201306;
  • 3. 上海海洋大学水产科学国家级实验教学示范中心, 上海, 201306
  • 收稿日期:  2018-09-19
基金项目:

十三五国家水体污染控制与治理科技重大专项（2017ZX07207002-03）资助.

摘要: 抗生素广泛应用于医疗、畜牧业和水产养殖业，但过量使用可对环境产生危害.磺胺类抗生素是一类常用的兽用抗生素，具有成本低、抗菌谱广等特性，能预防动物疾病和促进机体生长，被广泛应用于世界各地.然而，磺胺类抗生素难被机体吸收，常随粪便和尿液排出体外，继而发生一系列的环境行为，并造成环境污染.本文介绍了抗生素的分类、来源及危害，重点阐述了磺胺类抗生素的国内外污染现状、环境行为和毒性效应，为后续治理抗生素污染提供基础资料.

English Abstract

    全文HTML

参考文献 (85)

目录

/

返回文章
返回

Copyright © 2019 中国科学院生态环境研究中心