高级搜索

基于多壁碳纳米管表面印迹的己烯雌酚分子印迹电化学传感器制备及应用

,  ,  ,  ,  , 

downloadPDF

上一篇

下一篇

苏立强, 姜国强, 于亭亭, 兰志满, 王颖, 韩爽. 基于多壁碳纳米管表面印迹的己烯雌酚分子印迹电化学传感器制备及应用[J]. 环境化学, 2020, (12): 3511-3516. doi: 10.7524/j.issn.0254-6108.2019091101
引用本文: 苏立强, 姜国强, 于亭亭, 兰志满, 王颖, 韩爽. 基于多壁碳纳米管表面印迹的己烯雌酚分子印迹电化学传感器制备及应用[J]. 环境化学, 2020, (12): 3511-3516. doi: 10.7524/j.issn.0254-6108.2019091101
shu
SU Liqiang, JIANG Guoqiang, YU Tingting, LAN Zhiman, WANG Ying, HAN Shuang. Preparation and application of diethylstilbestrol molecularly imprinted electrochemical sensor based on multi-walled carbon nanotubes surface imprinting[J]. Environmental Chemistry, 2020, (12): 3511-3516. doi: 10.7524/j.issn.0254-6108.2019091101
Citation: SU Liqiang, JIANG Guoqiang, YU Tingting, LAN Zhiman, WANG Ying, HAN Shuang. Preparation and application of diethylstilbestrol molecularly imprinted electrochemical sensor based on multi-walled carbon nanotubes surface imprinting[J]. Environmental Chemistry, 2020, (12): 3511-3516. doi: 10.7524/j.issn.0254-6108.2019091101
shu

基于多壁碳纳米管表面印迹的己烯雌酚分子印迹电化学传感器制备及应用

  • 齐齐哈尔大学化学与化学工程学院, 齐齐哈尔, 161006

    • 通讯作者: 苏立强, E-mail: slq@163.com ; 
  • 基金项目:

    黑龙江省自然科学基金青年基金（QC2018073），黑龙江省教育厅科研项目（135109201）和齐齐哈尔大学研究生创新项目（YJSCX2018-016X）资助.

Preparation and application of diethylstilbestrol molecularly imprinted electrochemical sensor based on multi-walled carbon nanotubes surface imprinting

  • College of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar, 161006, China

    • Corresponding author: SU Liqiang, slq@163.com ; 
  • Fund Project: Supported by the Heilongjiang Natural Science Foundation Youth Fund (QC2018073),Heilongjiang Provincial Department of Education Research Project (135109201) and Qiqihar University Graduate Innovation Project (YJSCX2018-016X).

  • 摘要: 本文以丙烯酰胺功能化多壁碳纳米管为载体，以己烯雌酚（DES）为模板分子，采用表面印迹法制备了己烯雌酚分子印迹聚合物，将其滴涂在玻碳电极表面，构建分子印迹电化学传感器.采用循环伏安法（CV）和电化学阻抗谱（EIS）表征修饰电极.采用差分脉冲伏安法（DPV）对电极使用条件进行优化.结果表明，制备的传感器具有良好的选择性，在优化条件下，传感器电流响应值与己烯雌酚浓度（1.0×10-9—1.0×10-6 mol·L-1）呈良好的线性关系，将传感器用于牛奶样品中己烯雌酚的测定，加标回收率在96.8%—98.8%之间.
    Abstract: In this paper, the molecularly imprinted polymer of diethylstilbestrol was prepared by surface imprinting using acrylamide functionalized multi-walled carbon nanotubes as supporter, and diethylstilbestrol (DES) as template molecule. The molecularly imprinted electrochemical sensor was then constructed by dropping the obtained MIPs onto the surface of glassy carbon electrode (GCE). The modified electrode was characterized by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The woking conditions of electrode were optimized using differential pulse voltammetry (DPV). The results showed that the prepared sensor had good selectivity. Under the optimized conditions, the sensor current response value had a good linear relationship with the concentration of diethylstilbestrol(1.0×10-9—1.0×10-6 mol·L-1). The sensor was used for the determination of diethylstilbestrol in milk samples, and the recoveries were among 96.8% to 98.8%.
  • 加载中
  • [1] WANG X J, DING H, YU X R, et al. Characterization and application of molecularly imprinted polymer-coated quantum dots for sensitive fluorescent determination of diethylstilbestrol in water samples[J]. Talanta, 2019, 197:98-104.
    [2] ZHAO W R, KANG T F, LU L P, et al. Electrochemical magnetic imprinted sensor based on MWCNTs@CS/CTABr surfactant composites for sensitive sensing of diethylstilbestrol[J]. Journal of Electroanalytical Chemistry, 2018, 818:181-190.
    [3] BAI J L, ZHANG X Y, PENG Y, et al. Ultrasensitive sensing of diethylstilbestrol based on AuNPs/MWCNTs-CS composites coupling with sol-gel molecularly imprinted polymer as a recognition element of an electrochemical sensor[J]. Sensors & Actuators B Chemical, 2017, 238:420-426.
    [4] 中华人民共和国农业部.中华人民共和国农业部第235号公告[S].2002. Ministry of Agriculture of the People's Republic of China. Notice No. 235 of the Ministry of Agriculture of the People's Republic of China[S].2002

    (in Chinese).

    [5] 戚琦,黄闵,谢海华.离子液体分散液-液微萃取-高效液相色谱法测定牛奶中己烯雌酚[J]. 食品科学,2016,37(4):202-205.

    QI Q, HUANG W, XIE H H.Determination of diethylstilbestrol in milk by ionic liquid dispersion-liquid microextraction-high performance liquid chromatography[J]. Food Science and Technology, 2016,37(4):202-205(in Chinese).

    [6] 陈才军,周勇,陈翔,等.UPLC-MS/MS法测定美容养颜类保健食品中9种雌激素[J]. 食品工业,2017,38(12):292-295.

    CHEN C J, ZHOU Y, CHEN X, et al. Determination of 9 estrogens in beauty and beauty foods by UPLC-MS/MS method[J]. The Food Industry, 2017, 38(12):292-295(in Chinese).

    [7] 苏立强,张慧洁,姜国强,等.RAFT沉淀聚合法制备乙氧酰胺苯甲酯分子印迹材料及其应用[J]. 分析试验室,2018,37(8):927-931.

    SU L Q, ZHANG H J, JIANG G Q, et al. Preparation of ethoxylated benzyl ester molecularly imprinted material by RAFT precipitation polymerization and its application[J].Chinese Journal of Analysis Laboratory, 2018, 37(8):927-931(in Chinese).

    [8] 陈光浩,欧红香,余沛霖,等.多孔温敏四环素分子印迹吸附剂的制备及性能[J]. 环境化学,2018,37(7):1619-1627.

    CHEN G H, OU H X, YU P L, et al. Preparation and properties of porous temperature-sensitive tetracycline molecular imprinting adsorbent[J]. Environmental Chemistry, 2018, 37(7):1619-1627(in Chinese).

    [9] 李成,张雪娜,师耀龙,等.分子印迹固相萃取-气相色谱/质谱联用法测定污泥中多环芳烃[J]. 环境化学,2017,36(1):190-197.

    LI C, ZHANG X N, SHI Y L, et al. Determination of polycyclic aromatic hydrocarbons in sludge by molecularly imprinted solid phase extraction-gas chromatography/mass spectrometry[J]. Environmental Chemistry, 2017, 36(1):190-197(in Chinese).

    [10] HUANG X, WEI S L, YAO S, et al. Development of molecularly imprinted electrochemical sensor with reduced graphene oxide and titanium dioxide enhanced performance for the detection of toltrazuril in chicken muscle and egg[J]. Journal of Pharmaceutical and Biomedical Analysis,2019,164:607-614.
    [11] ALIZADEH T, ATASHI F, GANJALI M R. Molecularly imprinted polymer nano-sphere/multi-walled carbon nanotube coated glassy carbon electrode as an ultra-sensitive voltammetric sensor for picomolar level determination of RDX[J]. Talanta, 2019, 194:415-421.
    [12] 李颖,徐文凯,李苹,等.Fe3O4/MnO2掺杂石墨烯基分子印迹杂化材料用于水环境中17β-雌二醇的电化学传感检测[J]. 分析化学,2018,46(7):1047-1054.

    LI Y, XU W K, LI P, et al. Fe3O4/MnO2 doped graphene-based molecularly imprinted hybrid materials for electrochemical sensing of 17β-estradiol in aqueous environment[J]. Chinese Journal of Analytical Chemistry, 2018, 46(7):1047-1054(in Chinese).

    [13] HASHEMI M, NAZARI Z, BIGDELIFAM D. A molecularly imprinted polymer based on multiwalled carbon nanotubes for separation and spectrophotometric determination of L-cysteine[J]. Microchimica Acta, 2017, 184, 2523-2532.
    [14] NIE D, HAN Z, YU Y, et al. Composites of multiwalled carbon nanotubes/polyethyleneimine (MWCNTs/PEI) and molecularly imprinted polymers for dinitrotoluene recognition[J]. Sensors & Actuators B Chemical, 2015, 224:584-591.
    [15] 孙婷,张菁,刘云,等.HPLC法同时测定雌激素类药物尼尔雌醇片和己烯雌酚片中主药含量[J]. 中国药房,2019,30(4):469-472.

    SUN T, ZHANG J, LIU Y, et al. Simultaneous determination of main components in estrogenic hormone drug nilestriol tablets and diethylstilbestrol tablets by HPLC[J]. China Pharmacy, 2019, 30(4):469-472(in Chinese).

    [16] 张秋菊,曹林波,翁少梅,等.固相微萃取-高效液相色谱法测定牛奶和肉类中己烯雌酚、丙酸睾酮和双酚A[J]. 中国卫生检验杂志,2017,27(5):635-638.

    ZHANG Q J, CAO L B, WENG S M, et al. Determination of diethylstilbestrol, testosterone propionate and bisphenol A in milk and meat by solid phase micro-extraction and high-performance liquid chromatography[J]. Chinese Journal of Health Laboratory Technology, 2017, 27(5):635-638(in Chinese).

  • 加载中
WeChat 点击查看大图
计量
  • 文章访问数:  2097
  • HTML全文浏览数:  2097
  • PDF下载数:  27
  • 施引文献:  0
出版历程
  • 收稿日期:  2019-09-11
苏立强, 姜国强, 于亭亭, 兰志满, 王颖, 韩爽. 基于多壁碳纳米管表面印迹的己烯雌酚分子印迹电化学传感器制备及应用[J]. 环境化学, 2020, (12): 3511-3516. doi: 10.7524/j.issn.0254-6108.2019091101
引用本文: 苏立强, 姜国强, 于亭亭, 兰志满, 王颖, 韩爽. 基于多壁碳纳米管表面印迹的己烯雌酚分子印迹电化学传感器制备及应用[J]. 环境化学, 2020, (12): 3511-3516. doi: 10.7524/j.issn.0254-6108.2019091101
shu
SU Liqiang, JIANG Guoqiang, YU Tingting, LAN Zhiman, WANG Ying, HAN Shuang. Preparation and application of diethylstilbestrol molecularly imprinted electrochemical sensor based on multi-walled carbon nanotubes surface imprinting[J]. Environmental Chemistry, 2020, (12): 3511-3516. doi: 10.7524/j.issn.0254-6108.2019091101
Citation: SU Liqiang, JIANG Guoqiang, YU Tingting, LAN Zhiman, WANG Ying, HAN Shuang. Preparation and application of diethylstilbestrol molecularly imprinted electrochemical sensor based on multi-walled carbon nanotubes surface imprinting[J]. Environmental Chemistry, 2020, (12): 3511-3516. doi: 10.7524/j.issn.0254-6108.2019091101
shu

基于多壁碳纳米管表面印迹的己烯雌酚分子印迹电化学传感器制备及应用

    通讯作者: 苏立强, E-mail: slq@163.com ; 
  • 齐齐哈尔大学化学与化学工程学院, 齐齐哈尔, 161006
  • 收稿日期:  2019-09-11
基金项目:

黑龙江省自然科学基金青年基金（QC2018073），黑龙江省教育厅科研项目（135109201）和齐齐哈尔大学研究生创新项目（YJSCX2018-016X）资助.

摘要: 本文以丙烯酰胺功能化多壁碳纳米管为载体，以己烯雌酚（DES）为模板分子，采用表面印迹法制备了己烯雌酚分子印迹聚合物，将其滴涂在玻碳电极表面，构建分子印迹电化学传感器.采用循环伏安法（CV）和电化学阻抗谱（EIS）表征修饰电极.采用差分脉冲伏安法（DPV）对电极使用条件进行优化.结果表明，制备的传感器具有良好的选择性，在优化条件下，传感器电流响应值与己烯雌酚浓度（1.0×10-9—1.0×10-6 mol·L-1）呈良好的线性关系，将传感器用于牛奶样品中己烯雌酚的测定，加标回收率在96.8%—98.8%之间.

English Abstract

    全文HTML

参考文献 (16)

返回顶部

目录

/

返回文章
返回

Copyright © 2019 中国科学院生态环境研究中心