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白洋淀沉积物中抗生素的赋存特征与生态风险

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凌玉婷, 贲玉婕, 黄林艳, 张覃, 马小爽, 魏晓鸥, 赵亚娴. 白洋淀沉积物中抗生素的赋存特征与生态风险[J]. 生态毒理学报, 2025, 20(2): 122-136. doi: 10.7524/AJE.1673-5897.20241223001
引用本文: 凌玉婷, 贲玉婕, 黄林艳, 张覃, 马小爽, 魏晓鸥, 赵亚娴. 白洋淀沉积物中抗生素的赋存特征与生态风险[J]. 生态毒理学报, 2025, 20(2): 122-136. doi: 10.7524/AJE.1673-5897.20241223001
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LING Yuting, BEN Yujie, HUANG Linyan, ZHANG Qin, MA Xiaoshuang, WEI Xiaoou, ZHAO Yaxian. Antibiotics in the Sediment of the Baiyangdian Lake, China: Occurrence, Distribution and Ecological Risk[J]. Asian journal of ecotoxicology, 2025, 20(2): 122-136. doi: 10.7524/AJE.1673-5897.20241223001
Citation: LING Yuting, BEN Yujie, HUANG Linyan, ZHANG Qin, MA Xiaoshuang, WEI Xiaoou, ZHAO Yaxian. Antibiotics in the Sediment of the Baiyangdian Lake, China: Occurrence, Distribution and Ecological Risk[J]. Asian journal of ecotoxicology, 2025, 20(2): 122-136. doi: 10.7524/AJE.1673-5897.20241223001
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白洋淀沉积物中抗生素的赋存特征与生态风险

  • 1. 中国环境科学研究院, 北京 100012;

  • 2. 生态环境部环境发展中心环境标准样品研究所, 北京 100029;

  • 3. 生态环境部污染物计量和标准样品研究重点实验室, 北京 100029;

  • 4. 南方科技大学, 深圳 518055;

  • 5. 宁波东方理工大学, 宁波 315000

    • 作者简介: 凌玉婷(1999—)，女，硕士研究生，研究方向为新污染物环境行为与标准样品研究，E-mail:lingyt55@163.com
    通讯作者: 赵亚娴,E-mail:zhao.yaxian@ierm.com.cn
  • 基金项目:

    国家重点研发计划课题(2023YFF0724402)；生态环境部环境发展中心科技发展基金项目(ZRZXJJ-202304)

  • 中图分类号: X171.5

Antibiotics in the Sediment of the Baiyangdian Lake, China: Occurrence, Distribution and Ecological Risk

  • 1. Chinese Research Academy of Environmental Sciences, Beijing 100012, China;

  • 2. Institute for Environmental Reference Materials, Environment Development Centre of the Ministry of Ecology and Environment, Beijing 100029, China;

  • 3. Key Laboratory of Environmental Pollutant Metrology and Reference Materials, Ministry of Ecology and Environment, Beijing 100029, China;

  • 4. Southern University of Science and Technology, Shenzhen 518055, China;

  • 5. Eastern Institute of Technology, Ningbo (EIT), Ningbo 315000, China

    • Corresponding author: ZHAO Yaxian, zhao.yaxian@ierm.com.cn
  • Fund Project:

  • 摘要: 抗生素作为一类新污染物，对环境安全和人类健康构成潜在威胁。本研究采用固相萃取-高效液相色谱-三重四极杆串联质谱技术系统分析白洋淀区域淀区核心区、入淀河流及其河湖过渡区沉积物中5类抗生素(包括喹诺酮类、大环内酯类、四环素类、磺胺类和β-内酰胺类抗生素)，共87种抗生素的赋存特征，并采用风险商值法评估其生态风险。结果表明，抗生素在41个采样点中普遍检出，总浓度为1 043 ng·g-1(0.710~139 ng·g-1)，其中喹诺酮类抗生素的浓度占比最高(80.6%)，检出率为95.1%；在检出的抗生素中，以优先兽用抗生素为主(占比82.5%)，其次为人用抗生素；在空间分布上，府河及其过渡区的污染最为严重，淀区核心区、孝义河及其过渡区、白沟引河及其过渡区的浓度水平依次降低；与前期研究相比，白洋淀沉积物中抗生素的浓度呈下降趋势；结合抗生素用途、空间分布以及不同抗生素浓度分布的相关性分析可知，白洋淀沉积物中的抗生素主要来源于污水处理厂、水产养殖与未经处理的居民生活废水；风险商结果表明，氧氟沙星、林可霉素和环丙沙星分别有92.7%、51.2%和14.6%的采样点中RQ>0.1，对水生生物具有较高的生态风险；联合生态风险数据显示，白洋淀区域处于中高风险水平(联合风险商值为0.193~22.5)。本研究结果有助于深入了解抗生素在白洋淀地区的时空分布与生态风险，为制定科学有效的抗生素污染防治管控措施提供数据支持。
    Abstract: As emerging contaminants, the antibiotics pose a potential threat to ecological security and human health. This study investigated the occurrence, distribution of 87 antibiotics belonging to five major categories (quinolone, macrolide, tetracycline, sulfonamide, and β-lactams) in sediments from Baiyangdian Lake using the solid phase extraction coupled with high performance liquid chromatography-mass spectrometry. Additionally, their ecological risks to aquatic organisms were assessed via the RQ method. The study area was divided into the core area of Baiyangdian Lake, three rivers directly flowing into the lake and their river-lake transition area. The results showed that antibiotics were generally detected at 41 sampling sites, with a total concentration of 1 043 ng·g-1 (ranging from 0.710 to 139 ng·g-1). Quinolones dominated both in total concentration (80.6%) and detection frequency (95.1%). In terms of usage, priority veterinary antibiotics were the main ones (accounting for 82.5%), followed by human use antibiotics. There was significant difference of spatial distribution of antibiotics. The contamination level of antibiotics was highest in sediment of Fuhe River and its river-lake transition area, and the concentration in the core area of the lake, the Xiaoyi River and its transition area, and the Baigouyin River and its transition area decreased successively. Compared with previous studies, antibiotic residues in Baiyangdian sediments showed a declining trend. Based on the usage, spatial distribution, and correlation analysis of the distribution of individual antibiotic concentrations, it suggested that antibiotics in the sediments of Baiyangdian Lake mainly originated from sewage treatment plants, aquaculture, and untreated domestic wastewater. Risk assessment indicated that ofloxacin, lincomycin, and ciprofloxacin exceeded RQ thresholds (RQ > 0.1) at 92.7%, 51.2%, and 14.6% of sites, respectively, posing elevated ecological risks. From the perspective of combined ecological risk, the whole Baiyangdian Lake area was at a medium to high-risk level (with combined risk quotient values ranging from 0.193 to 22.5). These findings enhance understanding of antibiotic distribution and risks in Baiyangdian, supporting evidence-based strategies for pollution control.
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  • 收稿日期:  2024-12-23
凌玉婷, 贲玉婕, 黄林艳, 张覃, 马小爽, 魏晓鸥, 赵亚娴. 白洋淀沉积物中抗生素的赋存特征与生态风险[J]. 生态毒理学报, 2025, 20(2): 122-136. doi: 10.7524/AJE.1673-5897.20241223001
引用本文: 凌玉婷, 贲玉婕, 黄林艳, 张覃, 马小爽, 魏晓鸥, 赵亚娴. 白洋淀沉积物中抗生素的赋存特征与生态风险[J]. 生态毒理学报, 2025, 20(2): 122-136. doi: 10.7524/AJE.1673-5897.20241223001
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LING Yuting, BEN Yujie, HUANG Linyan, ZHANG Qin, MA Xiaoshuang, WEI Xiaoou, ZHAO Yaxian. Antibiotics in the Sediment of the Baiyangdian Lake, China: Occurrence, Distribution and Ecological Risk[J]. Asian journal of ecotoxicology, 2025, 20(2): 122-136. doi: 10.7524/AJE.1673-5897.20241223001
Citation: LING Yuting, BEN Yujie, HUANG Linyan, ZHANG Qin, MA Xiaoshuang, WEI Xiaoou, ZHAO Yaxian. Antibiotics in the Sediment of the Baiyangdian Lake, China: Occurrence, Distribution and Ecological Risk[J]. Asian journal of ecotoxicology, 2025, 20(2): 122-136. doi: 10.7524/AJE.1673-5897.20241223001
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白洋淀沉积物中抗生素的赋存特征与生态风险

    通讯作者: 赵亚娴,E-mail:zhao.yaxian@ierm.com.cn
    作者简介: 凌玉婷(1999—)，女，硕士研究生，研究方向为新污染物环境行为与标准样品研究，E-mail:lingyt55@163.com
  • 1. 中国环境科学研究院, 北京 100012;
  • 2. 生态环境部环境发展中心环境标准样品研究所, 北京 100029;
  • 3. 生态环境部污染物计量和标准样品研究重点实验室, 北京 100029;
  • 4. 南方科技大学, 深圳 518055;
  • 5. 宁波东方理工大学, 宁波 315000
  • 收稿日期:  2024-12-23
基金项目:

国家重点研发计划课题(2023YFF0724402)；生态环境部环境发展中心科技发展基金项目(ZRZXJJ-202304)

摘要: 抗生素作为一类新污染物，对环境安全和人类健康构成潜在威胁。本研究采用固相萃取-高效液相色谱-三重四极杆串联质谱技术系统分析白洋淀区域淀区核心区、入淀河流及其河湖过渡区沉积物中5类抗生素(包括喹诺酮类、大环内酯类、四环素类、磺胺类和β-内酰胺类抗生素)，共87种抗生素的赋存特征，并采用风险商值法评估其生态风险。结果表明，抗生素在41个采样点中普遍检出，总浓度为1 043 ng·g-1(0.710~139 ng·g-1)，其中喹诺酮类抗生素的浓度占比最高(80.6%)，检出率为95.1%；在检出的抗生素中，以优先兽用抗生素为主(占比82.5%)，其次为人用抗生素；在空间分布上，府河及其过渡区的污染最为严重，淀区核心区、孝义河及其过渡区、白沟引河及其过渡区的浓度水平依次降低；与前期研究相比，白洋淀沉积物中抗生素的浓度呈下降趋势；结合抗生素用途、空间分布以及不同抗生素浓度分布的相关性分析可知，白洋淀沉积物中的抗生素主要来源于污水处理厂、水产养殖与未经处理的居民生活废水；风险商结果表明，氧氟沙星、林可霉素和环丙沙星分别有92.7%、51.2%和14.6%的采样点中RQ>0.1，对水生生物具有较高的生态风险；联合生态风险数据显示，白洋淀区域处于中高风险水平(联合风险商值为0.193~22.5)。本研究结果有助于深入了解抗生素在白洋淀地区的时空分布与生态风险，为制定科学有效的抗生素污染防治管控措施提供数据支持。

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