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用平板双分子层脂膜模拟研究锌离子跨细胞膜的传递过程

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朱宪, 叶宇慧, 孙当如. 用平板双分子层脂膜模拟研究锌离子跨细胞膜的传递过程[J]. 环境化学, 2005, 24(5): 558-561.
引用本文: 朱宪, 叶宇慧, 孙当如. 用平板双分子层脂膜模拟研究锌离子跨细胞膜的传递过程[J]. 环境化学, 2005, 24(5): 558-561.
shu
ZHU Xian, YE Yu-hui, SUN Dang-ru. PREPARATION OF PLANAR BILAYER LIPID MEMBRANES AND ITS APPLICATION FOR RESEARCH ON Zn2+ TRANSFER ACROSS BLM[J]. Environmental Chemistry, 2005, 24(5): 558-561.
Citation: ZHU Xian, YE Yu-hui, SUN Dang-ru. PREPARATION OF PLANAR BILAYER LIPID MEMBRANES AND ITS APPLICATION FOR RESEARCH ON Zn2+ TRANSFER ACROSS BLM[J]. Environmental Chemistry, 2005, 24(5): 558-561.
shu

用平板双分子层脂膜模拟研究锌离子跨细胞膜的传递过程

  • 1.

    上海大学环境与化学工程学院, 上海, 201800

  • 基金项目:

    国家自然科学基金资助项目(批准号:20176026)

PREPARATION OF PLANAR BILAYER LIPID MEMBRANES AND ITS APPLICATION FOR RESEARCH ON Zn2+ TRANSFER ACROSS BLM

  • 1.

    School of Environmental and Chemical Engineering, Shanghai Univ ersity, Shanghai, 201800

  • Fund Project:

  • 摘要: 制备了氧化胆固醇-卵磷脂(脑磷脂)平板双分子层脂膜,研究了膜配方对双分子层脂膜的稳定性和离子传递性能的影响,得到了最佳制膜工艺,并建立了锌离子跨卵(脑)磷脂膜的吸附-扩散模型,其计算值与实验值基本吻合.
    Abstract: The planar bilayer lipid membranes(BLM)comprised by oxidated cholesterol a nd lecithin/cephalin have been made , Its stability and its ion penetrating ability also have been researched . The optimal technics of making membrane was co nfirmed . The transport process of simulating zinc across the membranes was stud ied .Finally, the adsorption-diffuse model has been founded , the calculated va lue based on this model tallied basically with the experimental value.
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  • [1] 周晴中,何艳梅,模拟生物膜的聚合单层、双层和脂质体 [J] .大学化学, 1994,9(1)∶25-30
    [2] 范玉贞,生物膜脂质液晶的结构、性质及功能 [J] .生物学教学,2000,25(4)∶2-4
    [3] Rush L Robinson, Alfred Strickholm , Oxidized Cholesterol Bilayers Dependence of Electrical Properties on Degree of Oxidation and Aging [J] .Biochimica et Biophysica Acta,1978,509∶9-20
    [4] 田心棣,人造双分子层膜[M] .北京:高等教育出版社, 1987,5-7
    [5] 解玉冰,马小军,王毓福等,生物微胶囊传递模型的研究[J] ,膜科学与技术, 1997,17(4)∶51-60
    [6] 陆小华,王俊,朱宇等,分子动力学模拟研究流体微观结构和扩散性质 [J] ,南京工业大学学报,2002,24(1)∶7-11
    [7] 朱宪,路琼华,李盘生等,乳状液膜分离Zn2+的界面传质阻力及传质模型[J] ,高校化学工程学报, 1996,10(1)∶31-35
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  • 收稿日期:  2004-10-07
朱宪, 叶宇慧, 孙当如. 用平板双分子层脂膜模拟研究锌离子跨细胞膜的传递过程[J]. 环境化学, 2005, 24(5): 558-561.
引用本文: 朱宪, 叶宇慧, 孙当如. 用平板双分子层脂膜模拟研究锌离子跨细胞膜的传递过程[J]. 环境化学, 2005, 24(5): 558-561.
shu
ZHU Xian, YE Yu-hui, SUN Dang-ru. PREPARATION OF PLANAR BILAYER LIPID MEMBRANES AND ITS APPLICATION FOR RESEARCH ON Zn2+ TRANSFER ACROSS BLM[J]. Environmental Chemistry, 2005, 24(5): 558-561.
Citation: ZHU Xian, YE Yu-hui, SUN Dang-ru. PREPARATION OF PLANAR BILAYER LIPID MEMBRANES AND ITS APPLICATION FOR RESEARCH ON Zn2+ TRANSFER ACROSS BLM[J]. Environmental Chemistry, 2005, 24(5): 558-561.
shu

用平板双分子层脂膜模拟研究锌离子跨细胞膜的传递过程

  • 1. 上海大学环境与化学工程学院, 上海, 201800
  • 收稿日期:  2004-10-07
基金项目:

国家自然科学基金资助项目(批准号:20176026)

摘要: 制备了氧化胆固醇-卵磷脂(脑磷脂)平板双分子层脂膜,研究了膜配方对双分子层脂膜的稳定性和离子传递性能的影响,得到了最佳制膜工艺,并建立了锌离子跨卵(脑)磷脂膜的吸附-扩散模型,其计算值与实验值基本吻合.

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