Environmental occurrence and biotransformation of perfluoroalkyl carboxylic acid precursors: Fluorotelomer alcohols

ZHANG Hongna; WEN Bei; ZHANG Shuzhen

doi:10.7524/j.issn.0254-6108.2020020101

2021 Volume 40 Issue 1

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ZHANG Hongna, WEN Bei, ZHANG Shuzhen. Environmental occurrence and biotransformation of perfluoroalkyl carboxylic acid precursors: Fluorotelomer alcohols[J]. Environmental Chemistry, 2021, (1): 65-82. doi: 10.7524/j.issn.0254-6108.2020020101

Citation:

ZHANG Hongna, WEN Bei, ZHANG Shuzhen. Environmental occurrence and biotransformation of perfluoroalkyl carboxylic acid precursors: Fluorotelomer alcohols[J]. Environmental Chemistry, 2021, (1): 65-82. doi: 10.7524/j.issn.0254-6108.2020020101

Environmental occurrence and biotransformation of perfluoroalkyl carboxylic acid precursors: Fluorotelomer alcohols

1. State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China;
2. State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong SAR, 999077, China;
3. University of Chinese Academy of Sciences, Beijing, 100049, China

Corresponding author: WEN Bei, bwen@rcees.ac.cn ;
Received Date: 01/02/2020

Fund Project: Supported by the National Natural Science Foundation of China (21537005, 21806134, 41671465).

Abstract

Perfluorocarboxylic acids (PFCAs) have received great regulatory attention from the government and international organizations due to their environmental persistence, bioaccumulation and potential toxicity. With the effective reduction of their production and emission in recent years, exploring the indirect sources of PFCAs has become increasingly important. Fluorotelomer alcohols (FTOHs) are important raw materials used to produce fluoropolymers and fluorosurfactants, which have been incorporated into a variety of consumer and industrial products. Moreover, FTOHs are also primary biotransformation intermediates of multiple fluorotelomer-based substances. Degradation of FTOHs has been widely considered as an additional source of PFCAs in the environment and biological species. After entering the environment, FTOHs can undergo long-range transport and can be transformed into polyfluorinated intermediates, and finally oxidized to different carbon-chain lengths of PFCAs. Recent studies also showed that polyfluorinated intermediate metabolites of FTOHs exhibited higher biotoxicity than PFCAs. Therefore, to accurately reveal the environmental and health risks of FTOHs, it is essential to understand their environmental levels and biotransformation routes. In this paper, the sources and physicochemical properties of FTOHs were introduced, the analytical methods and environmental occurrence of FTOHs were reviewed, and the biotransformation processes and toxic mechanisms of FTOHs were analyzed.
- FTOHs,
- PFCAs,
- environmental occurrence,
- biodegradation,
- toxic mechanism

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沈阳化工大学材料科学与工程学院沈阳 110142

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Environmental occurrence and biotransformation of perfluoroalkyl carboxylic acid precursors: Fluorotelomer alcohols

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